PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
17962358-10	2008	PDGF-BB, IL-1beta, and angiotensin II induced ROS production, which was abolished by DPI and apocynin.	diphenyleneiodonium	85-88	interleukin 1 beta	Rattus norvegicus	9-17	
17962358-11	2008	DPI inhibited PDGF-induced proliferation, IL-1beta-induced chemokine production, and expression of alpha-smooth muscle actin and collagen.	diphenyleneiodonium	0-3	interleukin 1 beta	Rattus norvegicus	42-50	
15390122-5	2004	Expression of IL-1beta, TNF-alpha, and iNOS in ganglioside-treated cells was significantly reduced in the presence of inhibitors of PKC (GF109203X, Go6976, Ro31-8220, and rottlerin) and NADPH oxidase (diphenyleneiodonium chloride [DPI]).	diphenyleneiodonium	201-229	interleukin 1 beta	Rattus norvegicus	14-22	
17151863-6	2007	However, palmitic acid or IL-1beta-dependent production was reduced after 24 h. Islet ROS production was significantly increased after incubation in elevated glucose for 1 h and was completely abolished by addition of diphenylene iodonium, an inhibitor of NADPH oxidase or by the oligonucleotide anti-p47(phox).	diphenyleneiodonium	218-238	interleukin 1 beta	Rattus norvegicus	26-34	
17151863-7	2007	Addition of 0.1 mmol/l palmitic acid or 5 ng/ml IL-1beta plus 5.6 mmol/l glucose also resulted in a significant increase in islet ROS production after 1 h, which was partially attenuated by diphenylene iodonium or the protein kinase C inhibitor GF109203X.	diphenyleneiodonium	190-210	interleukin 1 beta	Rattus norvegicus	48-56	
16778360-2	2006	IL-1beta mRNA induction by CA-G alpha13 was suppressed by diphenyleneiodonium (DPI), an NADPH oxidase inhibitor, but not by BAPTA-AM, an intracellular Ca2+ chelator.	diphenyleneiodonium	58-77	interleukin 1 beta	Rattus norvegicus	0-8	
16778360-2	2006	IL-1beta mRNA induction by CA-G alpha13 was suppressed by diphenyleneiodonium (DPI), an NADPH oxidase inhibitor, but not by BAPTA-AM, an intracellular Ca2+ chelator.	diphenyleneiodonium	79-82	interleukin 1 beta	Rattus norvegicus	0-8	
16393992-5	2006	IL-1beta and TNF-alpha rapidly stimulated the rate of hydrogen peroxide produced by isolated microglia, and this was inhibited by diphenylene iodonium, implying that the cytokines were acting directly on microglia to stimulate the NADPH oxidase.	diphenyleneiodonium	130-150	interleukin 1 beta	Rattus norvegicus	0-8	
15390122-5	2004	Expression of IL-1beta, TNF-alpha, and iNOS in ganglioside-treated cells was significantly reduced in the presence of inhibitors of PKC (GF109203X, Go6976, Ro31-8220, and rottlerin) and NADPH oxidase (diphenyleneiodonium chloride [DPI]).	diphenyleneiodonium	231-234	interleukin 1 beta	Rattus norvegicus	14-22	
15390122-9	2004	Furthermore, ganglioside-induced activation of NF-kappaB, an essential transcription factor that mediates the expression of IL-1beta, TNF-alpha, and iNOS, was reduced in the presence of GF109203X and DPI.	diphenyleneiodonium	200-203	interleukin 1 beta	Rattus norvegicus	124-132	
14755545-7	2004	Diphenylene iodonium (DPI), inhibitor of NAD(P)H oxidase, and tiron, superoxide scavenger, inhibited Ang II- and Ang II+ IL-1beta-stimulated increases in OPN mRNA.	diphenyleneiodonium	22-25	interleukin 1 beta	Rattus norvegicus	121-129	
14755545-12	2004	DPI almost completely inhibited Ang II + IL-1beta-stimulated activation of ERK1/2, while partially inhibiting JNKs.	diphenyleneiodonium	0-3	interleukin 1 beta	Rattus norvegicus	41-49	
14755545-7	2004	Diphenylene iodonium (DPI), inhibitor of NAD(P)H oxidase, and tiron, superoxide scavenger, inhibited Ang II- and Ang II+ IL-1beta-stimulated increases in OPN mRNA.	diphenyleneiodonium	0-20	interleukin 1 beta	Rattus norvegicus	121-129