PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12928590-6	2003	Diphenylene iodonium, an inhibitor of NADPH oxidase, significantly inhibited CMV-induced IL-8 production and promotion of serum-induced DNA synthesis.	diphenyleneiodonium	0-20	C-X-C motif chemokine ligand 8	Homo sapiens	89-93	
25822013-12	2015	Furthermore, LF82 inhibited mucin gene expression (MUC2 and MUC5AC) in T84 cells while increasing the chemotactic IL-8 expression, both in a DPI-sensitive manner.	diphenyleneiodonium	141-144	C-X-C motif chemokine ligand 8	Homo sapiens	114-118	
10837166-4	2000	Treatment of cells with diphenylene iodonium inhibited virus-induced oxidative stress and IL-8 elaboration, but allopurinol, ibuprofen, and rotenone had no effect.	diphenyleneiodonium	24-44	C-X-C motif chemokine ligand 8	Homo sapiens	90-94	
30861304-5	2019	Pre-treatment with the ROS inhibitors N-acetyl cysteine (NAC) and diphenyleneiodonium (DPI) partially attenuated CXCL8 and IL-6 responses to 200 microg/mL, but not to 100 microg/mL Si50.	diphenyleneiodonium	66-85	C-X-C motif chemokine ligand 8	Homo sapiens	113-118	
30861304-5	2019	Pre-treatment with the ROS inhibitors N-acetyl cysteine (NAC) and diphenyleneiodonium (DPI) partially attenuated CXCL8 and IL-6 responses to 200 microg/mL, but not to 100 microg/mL Si50.	diphenyleneiodonium	87-90	C-X-C motif chemokine ligand 8	Homo sapiens	113-118	
12208513-3	2002	The stimulating effects on IL-8 promoter and AP-1 were reduced by N-acetylcysteine, glutathione, diphenyleneiodonium, rotenone and antimycin A.	diphenyleneiodonium	97-116	C-X-C motif chemokine ligand 8	Homo sapiens	27-31	
15611265-5	2005	Moreover, normal neutrophils treated with catalase (H(2)O(2) scavenger) or diphenyleneiodonium chloride (NADPH oxidase inhibitor) exhibit IL-8 responses comparable to those of CGD neutrophils.	diphenyleneiodonium	75-103	C-X-C motif chemokine ligand 8	Homo sapiens	138-142	
24049649-5	2012	Nevertheless, several parameters participating in oxidative stress (increased ROS production and apoptosis, decreased total thiol content) were observed in IB3-1 cells cultured in hypertonic environment as compared to S9 cells and were inhibited by diphenyleneiodonium (DPI), a well-known inhibitor of NOXs; besides, increased production of the proinflammatory cytokines IL-6 and IL-8 by IB3-1 cells was also inhibited by DPI as compared to S9 cells.	diphenyleneiodonium	249-268	C-X-C motif chemokine ligand 8	Homo sapiens	380-384	
26634216-7	2015	Hydroxy-3-methoxyaceto-phenone (HMAP), diphenyleneiodonium (DPI), and siRNA Nox2 reduced the ROS and IL-8 release in neutrophils treated with fMLP.	diphenyleneiodonium	39-58	C-X-C motif chemokine ligand 8	Homo sapiens	101-105	
26634216-7	2015	Hydroxy-3-methoxyaceto-phenone (HMAP), diphenyleneiodonium (DPI), and siRNA Nox2 reduced the ROS and IL-8 release in neutrophils treated with fMLP.	diphenyleneiodonium	60-63	C-X-C motif chemokine ligand 8	Homo sapiens	101-105	
15364949-7	2004	The oxidative burst induced cell death within 6 h of IL-8 stimulation of these cells, which could be prevented in the presence of DPI.	diphenyleneiodonium	130-133	C-X-C motif chemokine ligand 8	Homo sapiens	53-57