PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21208554-9 2011 Pretreatment with antioxidants such as N-acetylcysteine and diphenyleneiodonium significantly inhibited the activation of p38 MAPK compared with LPS control (P<0.05). diphenyleneiodonium 60-79 mitogen activated protein kinase 14 Rattus norvegicus 122-125 17308014-11 2007 DPI and DETC blocked RI-induced p38 MAP kinase activation in response to vascular endothelial growth factor and RI. diphenyleneiodonium 0-3 mitogen activated protein kinase 14 Rattus norvegicus 32-35 11006268-13 2000 Diphenylene iodonium, a potent inhibitor of NADPH oxidase(s), and ascorbic acid, an effective free radical scavenger, suppressed TSH- or forskolin-stimulated p38-MAPK phosphorylation, indicating that the generation of reactive oxygen species plays a key role in signaling from cAMP to p38-MAPKs. diphenyleneiodonium 0-20 mitogen activated protein kinase 14 Rattus norvegicus 158-161 11006268-13 2000 Diphenylene iodonium, a potent inhibitor of NADPH oxidase(s), and ascorbic acid, an effective free radical scavenger, suppressed TSH- or forskolin-stimulated p38-MAPK phosphorylation, indicating that the generation of reactive oxygen species plays a key role in signaling from cAMP to p38-MAPKs. diphenyleneiodonium 0-20 mitogen activated protein kinase 14 Rattus norvegicus 285-294 15743761-2 2005 Among three MAPKs, c-Jun NH(2)-terminal kinase (JNK) and p38 MAPK required ROS production for activation, as an NADPH oxidase inhibitor, diphenyleneiodonium, inhibited the activation. diphenyleneiodonium 137-156 mitogen activated protein kinase 14 Rattus norvegicus 57-60 15743761-4 2005 Constitutively active Galpha(12)- or Galpha(13)-induced activation of JNK and p38 MAPK, but not extracellular signal-regulated kinase (ERK), was inhibited by diphenyleneiodonium. diphenyleneiodonium 158-177 mitogen activated protein kinase 14 Rattus norvegicus 78-81 19762685-5 2009 Oxidative stress induced by microinjection of angiotensin II into RVLM augmented UCP2 mRNA or protein expression in RVLM, which was antagonized by comicroinjection of NADPH oxidase inhibitor (diphenyleneiodonium chloride), superoxide dismutase mimetic (tempol), or p38 mitogen-activated protein kinase inhibitor (SB203580) but not by extracellular signal-regulated kinase 1/2 inhibitor (U0126). diphenyleneiodonium 192-220 mitogen activated protein kinase 14 Rattus norvegicus 265-268