PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21327719-4	2011	Diphenylene iodonium (DPI) is known as an inhibitor of complex I in the mitochondrial respiratory chain, and it was also found to almost completely suppress the induction of NOX1 mRNA and the phosphorylation of activating transcription factor (ATF-1) by PGF2alpha or PDGF in a rat VSMC cell line.	diphenyleneiodonium	0-20	NADPH oxidase 1	Rattus norvegicus	174-178	
27816504-7	2017	NOX, specifically NOX1 was found to be an important cellular source of superoxide through experiments with the NOX inhibitors diphenyleneiodonium (DPI) and VAS2870 as well as isoform-specific NOX knockdown.	diphenyleneiodonium	126-145	NADPH oxidase 1	Rattus norvegicus	18-22	
27816504-7	2017	NOX, specifically NOX1 was found to be an important cellular source of superoxide through experiments with the NOX inhibitors diphenyleneiodonium (DPI) and VAS2870 as well as isoform-specific NOX knockdown.	diphenyleneiodonium	147-150	NADPH oxidase 1	Rattus norvegicus	18-22	
23114967-6	2013	Our results show that free heme evokes intracellular reactive oxygen species (ROS) production by IEC 6 cells, which is inhibited both by pharmacological inhibition with diphenyleneiodonium (10 muM), a NADPHox inhibitor, and small interfering RNA-mediated suppression of NOX1, a constitutive NADPHox isoform present in intestinal epithelial cells.	diphenyleneiodonium	169-188	NADPH oxidase 1	Rattus norvegicus	270-274	
21327719-4	2011	Diphenylene iodonium (DPI) is known as an inhibitor of complex I in the mitochondrial respiratory chain, and it was also found to almost completely suppress the induction of NOX1 mRNA and the phosphorylation of activating transcription factor (ATF-1) by PGF2alpha or PDGF in a rat VSMC cell line.	diphenyleneiodonium	22-25	NADPH oxidase 1	Rattus norvegicus	174-178	
21327719-5	2011	In this study, we found that the Ald-induced phosphorylation of ATF-1 and NOX1 expression was significantly suppressed by DPI.	diphenyleneiodonium	122-125	NADPH oxidase 1	Rattus norvegicus	74-78	
17435218-4	2007	In this study, however, we demonstrate that Rho is inactivated in K-Ras-transformed normal rat kidney cells, and that abrogation of Nox1-generated ROS by Nox1 small interference RNAs or diphenyleneiodonium restores Rho activation, suggesting that Nox1-generated oxidants mediate down-regulation of the Rho activity.	diphenyleneiodonium	186-205	NADPH oxidase 1	Rattus norvegicus	132-136	
18454179-2	2008	Here we describe that ablation of the Nox1 activity by Nox1 small-interference RNAs (siRNAs) or diphenylene iodonium (DPI) inhibited synthesis of both VEGF proteins and VEGF mRNAs in K-Ras transformed normal rat kidney (KNRK) cells.	diphenyleneiodonium	96-116	NADPH oxidase 1	Rattus norvegicus	38-42	
18454179-2	2008	Here we describe that ablation of the Nox1 activity by Nox1 small-interference RNAs (siRNAs) or diphenylene iodonium (DPI) inhibited synthesis of both VEGF proteins and VEGF mRNAs in K-Ras transformed normal rat kidney (KNRK) cells.	diphenyleneiodonium	118-121	NADPH oxidase 1	Rattus norvegicus	38-42	
15491278-3	2005	We found DPI (diphenylene iodonium), an inhibitor of flavoproteins, including NADPH oxidase itself, almost completely suppressed induction of NOX1 mRNA by PGF2alpha or PDGF in a rat vascular smooth muscle cell line, A7r5.	diphenyleneiodonium	9-12	NADPH oxidase 1	Rattus norvegicus	142-146	
15491278-3	2005	We found DPI (diphenylene iodonium), an inhibitor of flavoproteins, including NADPH oxidase itself, almost completely suppressed induction of NOX1 mRNA by PGF2alpha or PDGF in a rat vascular smooth muscle cell line, A7r5.	diphenyleneiodonium	14-34	NADPH oxidase 1	Rattus norvegicus	142-146	
15491278-4	2005	Exploration into the site of action of DPI using various inhibitors suggested the involvement of mitochondrial oxidative phosphorylation in PGF2alpha- or PDGF-induced increase in NOX1 mRNA.	diphenyleneiodonium	39-42	NADPH oxidase 1	Rattus norvegicus	179-183