PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16776966-7	2006	AngII significantly activated ERK1/2, JNK and P38 expressions and only JNK activation could be inhibited by Que and DPI.	diphenyleneiodonium	116-119	mitogen-activated protein kinase 8	Rattus norvegicus	71-74	
18754815-6	2009	Diphenyleneiodonium (DPI), a flavoprotein inhibitor used as NADPH oxidase inhibitor, prevented I/R-induced ROS formation in treated cells, together with the related lipoperoxidative damage, and JNK phosphorylation without affecting ERK activation, resulting in protection against cell death.	diphenyleneiodonium	0-19	mitogen-activated protein kinase 8	Rattus norvegicus	194-197	
18754815-6	2009	Diphenyleneiodonium (DPI), a flavoprotein inhibitor used as NADPH oxidase inhibitor, prevented I/R-induced ROS formation in treated cells, together with the related lipoperoxidative damage, and JNK phosphorylation without affecting ERK activation, resulting in protection against cell death.	diphenyleneiodonium	21-24	mitogen-activated protein kinase 8	Rattus norvegicus	194-197	
25681429-8	2015	The reactive oxygen species (ROS) inhibitors N-acetylcysteine (NAC), diphenyleneiodonium (DPI), and Tempol also diminished MCP-1 upregulation and JNK activation induced by ADP.	diphenyleneiodonium	69-88	mitogen-activated protein kinase 8	Rattus norvegicus	146-149	
25681429-8	2015	The reactive oxygen species (ROS) inhibitors N-acetylcysteine (NAC), diphenyleneiodonium (DPI), and Tempol also diminished MCP-1 upregulation and JNK activation induced by ADP.	diphenyleneiodonium	90-93	mitogen-activated protein kinase 8	Rattus norvegicus	146-149	
19202317-9	2009	We also confirmed that PDGF-induced JNK and Akt activations were inhibited by antioxidants, N-acetylcysteine and diphenyleneiodonium chloride, in RASMCs.	diphenyleneiodonium	113-141	mitogen-activated protein kinase 8	Rattus norvegicus	36-39	
16143311-7	2005	Diphenyleneiodonium (DPI), an inhibitor of NADPH oxidase, inhibited ROS generation, apoptotic cell death, caspase-3 activation and JNK activation.	diphenyleneiodonium	0-19	mitogen-activated protein kinase 8	Rattus norvegicus	131-134	
16143311-7	2005	Diphenyleneiodonium (DPI), an inhibitor of NADPH oxidase, inhibited ROS generation, apoptotic cell death, caspase-3 activation and JNK activation.	diphenyleneiodonium	21-24	mitogen-activated protein kinase 8	Rattus norvegicus	131-134	
15743761-2	2005	Among three MAPKs, c-Jun NH(2)-terminal kinase (JNK) and p38 MAPK required ROS production for activation, as an NADPH oxidase inhibitor, diphenyleneiodonium, inhibited the activation.	diphenyleneiodonium	137-156	mitogen-activated protein kinase 8	Rattus norvegicus	19-46	
15743761-2	2005	Among three MAPKs, c-Jun NH(2)-terminal kinase (JNK) and p38 MAPK required ROS production for activation, as an NADPH oxidase inhibitor, diphenyleneiodonium, inhibited the activation.	diphenyleneiodonium	137-156	mitogen-activated protein kinase 8	Rattus norvegicus	48-51	
15743761-4	2005	Constitutively active Galpha(12)- or Galpha(13)-induced activation of JNK and p38 MAPK, but not extracellular signal-regulated kinase (ERK), was inhibited by diphenyleneiodonium.	diphenyleneiodonium	158-177	mitogen-activated protein kinase 8	Rattus norvegicus	70-73	
12193730-6	2002	Incubation of GECs with complement stimulated production of superoxide, and pretreatment with the antioxidants, N-acetylcysteine, glutathione, and alpha-tocopherol as well as with diphenylene iodonium, an inhibitor of the NADPH oxidase, inhibited complement-induced JNK activation.	diphenyleneiodonium	180-200	mitogen-activated protein kinase 8	Rattus norvegicus	266-269	
10807739-6	2000	JNK and ERK were activated by ET-1 binding to a single receptor (ET-1A) but differed in their downstream mechanisms: only JNK activation was sensitive to the radical scavenger N-acetylcysteine and diphenylene iodonium, an inhibitor of NADPH oxidase, indicating a role for ROS.	diphenyleneiodonium	197-217	mitogen-activated protein kinase 8	Rattus norvegicus	0-3	
10807739-6	2000	JNK and ERK were activated by ET-1 binding to a single receptor (ET-1A) but differed in their downstream mechanisms: only JNK activation was sensitive to the radical scavenger N-acetylcysteine and diphenylene iodonium, an inhibitor of NADPH oxidase, indicating a role for ROS.	diphenyleneiodonium	197-217	mitogen-activated protein kinase 8	Rattus norvegicus	122-125