PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33575163-13 2021 Compared with the LPS group, APS pretreatment could inhibit the expression of inflammatory factors including TNF-alpha, IL-1 beta, IL-6, and IL-8 (all P < 0.05), reducing the number of apoptotic cells (P < 0.05), suppressing the expression of caspase-3, caspase-9, and Bax, but upregulating the expression levels of Bcl-2. aps 29-32 interleukin 6 Mus musculus 131-135 30590152-6 2019 The secretion and gene expression of NO/iNOS, IL-6 and TNF-alpha in APS-induced macrophage cell were significantly enhanced. aps 68-71 interleukin 6 Mus musculus 46-50 30590152-9 2019 Therefore, we demonstrated that APS could improve the immune functions of RAW 264.7 macrophages cells by promoting the cell viability and increasing secretion and gene expressions of NO/iNOS, IL-6 and TNF-alpha through the MAPK and NF-kappaB signaling pathways. aps 32-35 interleukin 6 Mus musculus 192-196 34289209-6 2021 Consistent with the changes in MDSCs, the serum level of IL-6, IL-1beta was the lowest in the APS group. aps 94-97 interleukin 6 Mus musculus 57-61