PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
32800555-4	2020	APS treatment significantly increased the expression of Nrf2 in the nucleus but decreased its expression in the cytoplasm, and restored the expression levels of Keap1, SOD, GSH-Px and MDA.	aps	0-3	nuclear factor, erythroid derived 2, like 2	Mus musculus	56-60	
32800555-5	2020	When APP/PS1 mice were treated with APS and injected with Nrf2 siRNA, the down-regulation of Nrf2 expression significantly blocked the regulation of APS on oxidative stress.	aps	36-39	nuclear factor, erythroid derived 2, like 2	Mus musculus	93-97	
32800555-5	2020	When APP/PS1 mice were treated with APS and injected with Nrf2 siRNA, the down-regulation of Nrf2 expression significantly blocked the regulation of APS on oxidative stress.	aps	149-152	nuclear factor, erythroid derived 2, like 2	Mus musculus	58-62	
32800555-5	2020	When APP/PS1 mice were treated with APS and injected with Nrf2 siRNA, the down-regulation of Nrf2 expression significantly blocked the regulation of APS on oxidative stress.	aps	149-152	nuclear factor, erythroid derived 2, like 2	Mus musculus	93-97	
32800555-7	2020	APS treatment significantly improved the cognitive ability of APP/PS1 mice, reduced apoptosis and the accumulation of Abeta, but the above effects of APS were blocked by Nrf2 siRNA injection.	aps	0-3	nuclear factor, erythroid derived 2, like 2	Mus musculus	170-174	
32800555-7	2020	APS treatment significantly improved the cognitive ability of APP/PS1 mice, reduced apoptosis and the accumulation of Abeta, but the above effects of APS were blocked by Nrf2 siRNA injection.	aps	150-153	nuclear factor, erythroid derived 2, like 2	Mus musculus	170-174	
32800555-8	2020	Therefore, APS can activate Nrf2 pathway to improve the physiological function of AD mice, which may have important clinical application value.	aps	11-14	nuclear factor, erythroid derived 2, like 2	Mus musculus	28-32	
34229016-8	2021	The inhibition of acute UC in mice was correlated with the APs-mediated effects on improving the expression of ZO-1, occludin, Nrf2, HO-I, and NQO1.	aps	59-62	nuclear factor, erythroid derived 2, like 2	Mus musculus	127-131	
34229016-9	2021	Thus, APs effectively promoted the intestinal barrier via Nrf2/HO-1 signaling pathway and SCFAs metabolism, effectively ameliorating acute colitis in mice.	aps	6-9	nuclear factor, erythroid derived 2, like 2	Mus musculus	58-62