PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12679518-7 2003 The 14 most active sequences allowed growth in the presence of 0.1-0.6 mM 3-amino-1,2,4-triazole, a competitive inhibitor of the HIS3 gene product. Amitrole 74-96 imidazoleglycerol-phosphate dehydratase HIS3 Saccharomyces cerevisiae S288C 129-133 3280970-1 1988 In Saccharomyces cerevisiae, 3-amino-1,2,4-triazole (aminotriazole) competitively inhibits the activity of imidazoleglycerolphosphate dehydratase, the product of the HIS3 gene. Amitrole 29-51 imidazoleglycerol-phosphate dehydratase HIS3 Saccharomyces cerevisiae S288C 166-170 3280970-1 1988 In Saccharomyces cerevisiae, 3-amino-1,2,4-triazole (aminotriazole) competitively inhibits the activity of imidazoleglycerolphosphate dehydratase, the product of the HIS3 gene. Amitrole 53-66 imidazoleglycerol-phosphate dehydratase HIS3 Saccharomyces cerevisiae S288C 166-170 11162372-6 2000 Upon introduction of parasite CpMBF1 into S. cerevisiae, 3-amino triazole resistance of the MBF1-deficient strain was restored to wild-type levels, and Northern blot analysis revealed that CpMBF1 was able to activate HIS3 transcription in response to histidine starvation. Amitrole 57-73 imidazoleglycerol-phosphate dehydratase HIS3 Saccharomyces cerevisiae S288C 217-221 9819425-6 1998 Of the putative interacting genes examined, PBP1 promoted the highest level of resistance to 3-aminotriazole (>100 mM) in constructs in which HIS3 was used as a reporter. Amitrole 93-108 imidazoleglycerol-phosphate dehydratase HIS3 Saccharomyces cerevisiae S288C 145-149 8246886-5 1993 Further experiments demonstrated the ability of O2 to rescue a gcn4 mutant grown in the presence of aminotriazole, an inhibitor of the HIS3 gene product, suggesting that O2 activates the HIS3 gene, gene normally under control of GCN4. Amitrole 100-113 imidazoleglycerol-phosphate dehydratase HIS3 Saccharomyces cerevisiae S288C 135-139 8246886-5 1993 Further experiments demonstrated the ability of O2 to rescue a gcn4 mutant grown in the presence of aminotriazole, an inhibitor of the HIS3 gene product, suggesting that O2 activates the HIS3 gene, gene normally under control of GCN4. Amitrole 100-113 imidazoleglycerol-phosphate dehydratase HIS3 Saccharomyces cerevisiae S288C 187-191