PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30450033-11	2018	The lactulose pretreatment increased mRNA expressions of Nrf2, p62, and HO-1.	Lactulose	4-13	NFE2 like bZIP transcription factor 2	Rattus norvegicus	57-61	
30450033-12	2018	These findings suggest that lactulose pretreatment can alleviate METH-induced neurotoxicity through suppressing neuroinflammation and oxidative stress, which might be attributed to the activation of the Nrf2/HO-1 axis.	Lactulose	28-37	NFE2 like bZIP transcription factor 2	Rattus norvegicus	203-207	
23954468-11	2013	Lactulose orally administered activated the expression of NF-E2-related factor 2 (Nrf2) in the brain as verified by RT-PCR and Western blot.	Lactulose	0-9	NFE2 like bZIP transcription factor 2	Rattus norvegicus	58-80	
23954468-11	2013	Lactulose orally administered activated the expression of NF-E2-related factor 2 (Nrf2) in the brain as verified by RT-PCR and Western blot.	Lactulose	0-9	NFE2 like bZIP transcription factor 2	Rattus norvegicus	82-86	
23954468-14	2013	Lactulose intragastrically administered possessed neuroprotective effects on cerebral I/R injury in rats, which could be attributed to hydrogen production by the fermentation of lactulose through intestinal bacteria and Nrf2 activation.	Lactulose	0-9	NFE2 like bZIP transcription factor 2	Rattus norvegicus	220-224