PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34664730-1 2021 BACKGROUND: We have recently reported a mouse model of PNAC in which combining intestinal inflammation and PN infusion results in cholestasis, hepatic macrophage activation, and transcriptional suppression of canalicular bile acid transporter Abcb11, bilirubin exporter Abcc2, and sterol transporters Abcg5/8. pnac 55-59 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 Mus musculus 270-275 34664730-10 2021 CONCLUSIONS: TNFalpha is a key mediator in the pathogenesis of PNAC through suppression of hepatocyte Abcb11, Abcc2 and Abcg5/8. pnac 63-67 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 Mus musculus 110-115