PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30056145-4	2018	MDA and protein carbonyl content of liver homogenate were induced by CCl4 and anthocyanin treated group reduced both significantly.Monocyte chemoattractant protein 1 (MCP1), Interleukin 1 beta (IL1beta), macrophage inflammatory protein 2 (MIP-2) were induced by CCl4 were attenuated by anthocyanin.	Anthocyanins	78-89	interleukin 1 beta	Mus musculus	194-201	
28208071-8	2017	Additionally, anthocyanin significantly reduced the expression and secretion of tumor necrosis factor-alpha (TNF-alpha), interleukin-1beta (IL-1beta) and interleukin-6 (IL-6) in the calvaria of CoCrMo-stimulated mice.	Anthocyanins	14-25	interleukin 1 beta	Mus musculus	121-138	
27167130-8	2017	ANT showed a protective effect on the increase in the pro-inflammatory cytokines content, especially Interleukin (IL)-1beta, tumoral necrosis factor-alpha and on the reduction of IL-10 induced by LPS.	Anthocyanins	0-3	interleukin 1 beta	Mus musculus	101-123	
28208071-8	2017	Additionally, anthocyanin significantly reduced the expression and secretion of tumor necrosis factor-alpha (TNF-alpha), interleukin-1beta (IL-1beta) and interleukin-6 (IL-6) in the calvaria of CoCrMo-stimulated mice.	Anthocyanins	14-25	interleukin 1 beta	Mus musculus	140-148	
23344054-4	2013	Our results showed that anthocyanins significantly inhibited LPS-induced pro-inflammatory mediators, such as nitric oxide (NO) and prostaglandin E(2), and pro-inflammatory cytokines including tumor necrosis factor (TNF)-alpha and interleukin (IL)-1beta, without significant cytotoxicity.	Anthocyanins	24-36	interleukin 1 beta	Mus musculus	230-252	
24565673-5	2014	Interleukin 1beta (IL-1beta) messenger RNA (mRNA) levels were significantly decreased by all berry anthocyanins at 10 mug/ml or higher.	Anthocyanins	99-111	interleukin 1 beta	Mus musculus	0-17	
24565673-5	2014	Interleukin 1beta (IL-1beta) messenger RNA (mRNA) levels were significantly decreased by all berry anthocyanins at 10 mug/ml or higher.	Anthocyanins	99-111	interleukin 1 beta	Mus musculus	19-27	
24565673-10	2014	However, in the BMM from Nrf2(-/-) mice, the anthocyanin fractions were able to significantly decrease IL-1beta mRNA despite the fact that ROS levels were not significantly affected.	Anthocyanins	45-56	interleukin 1 beta	Mus musculus	103-111	
27522965-7	2016	The immunoblotting and morphological results showed that anthocyanins treatment significantly reduced LPS-induced-ROS-mediated neuroinflammation through inhibition of various inflammatory mediators, such as IL-1beta, TNF-alpha and the transcription factor NF-kB.	Anthocyanins	57-69	interleukin 1 beta	Mus musculus	207-215	
23344054-5	2013	Anthocyanins also downregulated excessive expression of inducible NO synthase, cyclooxygenase-2, TNF-alpha, and IL-1beta in LPS-stimulated BV2 cells.	Anthocyanins	0-12	interleukin 1 beta	Mus musculus	112-120