PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28940939-1 2018 Previous studies have shown that GLABRA3 (AtGL3), a bHLH transcription factor, plays essential roles in anthocyanin biosynthesis and trichome formation in Arabidopsis thaliana. Anthocyanins 104-115 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 33-40 29944442-0 2018 Effect of phosphate deficiency-induced anthocyanin accumulation on the expression of Solanum lycopersicum GLABRA3 (SlGL3) in tomato. Anthocyanins 39-50 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 106-113 29944442-1 2018 In Arabidopsis thaliana, the bHLH transcription factor, GLABRA3 (AtGL3), is an important regulator of epidermal cell differentiation and positively controls anthocyanin accumulation. Anthocyanins 157-168 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 56-63 29944442-1 2018 In Arabidopsis thaliana, the bHLH transcription factor, GLABRA3 (AtGL3), is an important regulator of epidermal cell differentiation and positively controls anthocyanin accumulation. Anthocyanins 157-168 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 65-70 29944442-2 2018 In contrast, we previously showed that Solanum lycopersicum GLABRA3 (SlGL3), the AtGL3 homolog, suppressed anthocyanin accumulation in Arabidopsis. Anthocyanins 107-118 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 60-67 29944442-2 2018 In contrast, we previously showed that Solanum lycopersicum GLABRA3 (SlGL3), the AtGL3 homolog, suppressed anthocyanin accumulation in Arabidopsis. Anthocyanins 107-118 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 81-86 28940939-1 2018 Previous studies have shown that GLABRA3 (AtGL3), a bHLH transcription factor, plays essential roles in anthocyanin biosynthesis and trichome formation in Arabidopsis thaliana. Anthocyanins 104-115 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 42-47 28940939-5 2018 Ectopic expression of the BnGL3-1 gene in the A. thaliana gl3-3 mutant resulted in levels of anthocyanins and numbers of trichomes in true leaves that were higher than in wild-type plants. Anthocyanins 93-105 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 58-61 28940939-6 2018 Moreover, overexpression of BnGL3-1 in gl3-3 compensated for the promotion and repression of genes involved in anthocyanin biosynthesis and trichome formation, respectively, that has been reported in gl3-3 young shoots and expanding true leaves. Anthocyanins 111-122 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 39-42 28940939-6 2018 Moreover, overexpression of BnGL3-1 in gl3-3 compensated for the promotion and repression of genes involved in anthocyanin biosynthesis and trichome formation, respectively, that has been reported in gl3-3 young shoots and expanding true leaves. Anthocyanins 111-122 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 200-203 28940939-7 2018 This study provides new insights into GL3 function in anthocyanin biosynthesis and trichome formation in crucifers, and represents a promising target for genetic manipulation of B. napus. Anthocyanins 54-65 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 38-41 28216162-0 2017 Genome-wide identification of GLABRA3 downstream genes for anthocyanin biosynthesis and trichome formation in Arabidopsis. Anthocyanins 59-70 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 30-37 28216162-1 2017 GLABRA3 (GL3), a bHLH transcription factor, has previously proved to be involved in anthocyanin biosynthesis and trichome formation in Arabidopsis, however, its downstream targeted genes are still largely unknown. Anthocyanins 84-95 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 0-7 28216162-1 2017 GLABRA3 (GL3), a bHLH transcription factor, has previously proved to be involved in anthocyanin biosynthesis and trichome formation in Arabidopsis, however, its downstream targeted genes are still largely unknown. Anthocyanins 84-95 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 9-12 28216162-3 2017 New downstream targeted genes of GL3 for anthocyanin biosynthesis and trichome formation were identified in young shoots and expanding true leaves by RNA sequencing. Anthocyanins 41-52 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 33-36 28216162-5 2017 This study provides new clues to further understand the GL3-mediated regulatory network of anthocyanin biosynthesis and trichome formation in Arabidopsis. Anthocyanins 91-102 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 56-59 25659750-1 2015 The two Arabidopsis basic-helix-loop-helix transcription factors GLABRA3 (GL3) and ENHANCER OF GLABRA3 (EGL3) are positive regulators of anthocyanin biosynthesis, and form protein complexes (MBW complexes) with various R2R3 MYB transcription factors and a WD40 repeat protein TRANSPARENT TESTA GLABROUS1 (TTG1). Anthocyanins 137-148 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 65-72 25604992-2 2015 The R2R3 MYB-activator production of anthocyanin pigment 1 (PAP1)/MYB75 plays a major role in anthocyanin biosynthesis in Arabidopsis in combination with one of three bHLH activators including transparent test 8 (TT8), enhancer of glabra3 (EGL3), glabra3 (GL3), and the WD-repeat transcription factor transparent testa 1 (TTG1), forming ternary MYB-basic HLH-WD40 complexes. Anthocyanins 37-48 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 231-238 25604992-2 2015 The R2R3 MYB-activator production of anthocyanin pigment 1 (PAP1)/MYB75 plays a major role in anthocyanin biosynthesis in Arabidopsis in combination with one of three bHLH activators including transparent test 8 (TT8), enhancer of glabra3 (EGL3), glabra3 (GL3), and the WD-repeat transcription factor transparent testa 1 (TTG1), forming ternary MYB-basic HLH-WD40 complexes. Anthocyanins 37-48 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 247-254 25604992-2 2015 The R2R3 MYB-activator production of anthocyanin pigment 1 (PAP1)/MYB75 plays a major role in anthocyanin biosynthesis in Arabidopsis in combination with one of three bHLH activators including transparent test 8 (TT8), enhancer of glabra3 (EGL3), glabra3 (GL3), and the WD-repeat transcription factor transparent testa 1 (TTG1), forming ternary MYB-basic HLH-WD40 complexes. Anthocyanins 37-48 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 241-244 25659750-4 2015 Here the GL3 and EGL3 proteins were characterized with respect to their affinities for PRODUCTION OF ANTHOCYANIN PIGMENT2 (PAP2), a R2R3-MYB which is induced by nitrogen depletion and is part of MBW complexes promoting anthocyanin synthesis. Anthocyanins 219-230 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 9-12 25659750-5 2015 GL3 and EGL3 were also tested for their binding to MYBL2, a negative regulator of anthocyanin synthesis and MBW complexes. Anthocyanins 82-93 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 0-3 25659750-9 2015 The present work underpins that GL3 is essential for anthocyanin accumulation under nitrogen depletion not only due to transcriptional activation, but also because of binding properties to proteins promoting or inhibiting the activity of the MBW complex. Anthocyanins 53-64 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 32-35 25659750-1 2015 The two Arabidopsis basic-helix-loop-helix transcription factors GLABRA3 (GL3) and ENHANCER OF GLABRA3 (EGL3) are positive regulators of anthocyanin biosynthesis, and form protein complexes (MBW complexes) with various R2R3 MYB transcription factors and a WD40 repeat protein TRANSPARENT TESTA GLABROUS1 (TTG1). Anthocyanins 137-148 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 74-77 25659750-2 2015 In earlier studies, GL3, in contrast to EGL3, was shown to be essential for accumulation of anthocyanins in response to nitrogen depletion. Anthocyanins 92-104 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 20-23 26039466-2 2015 CPC and GL3 are involved in root-hair differentiation, trichome initiation and anthocyanin biosynthesis in Arabidopsis epidermal cells. Anthocyanins 79-90 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 8-11 26039466-3 2015 Previously, we showed that CPC and GL3 also influence anthocyanin accumulation in tomato. Anthocyanins 54-65 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 35-38 26039466-5 2015 In contrast, introduction of GL3::GL3 strongly enhances anthocyanin accumulation in cotyledons, leaves and stems of tomato. Anthocyanins 56-67 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 29-32 26039466-5 2015 In contrast, introduction of GL3::GL3 strongly enhances anthocyanin accumulation in cotyledons, leaves and stems of tomato. Anthocyanins 56-67 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 34-37 26039466-6 2015 In this study, we investigated the effect of CPC and GL3 on anthocyanin accumulation in the epidermis of tomato fruit. Anthocyanins 60-71 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 53-56 24370633-2 2014 The red cells are metabolically programmed to produce high levels of anthocyanins by a WD40-bHLH-MYB complex that is composed of the TTG1, TT8/GL3 and PAP1 transcription factors. Anthocyanins 69-81 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 143-146 25268379-0 2014 Arabidopsis CAPRICE (MYB) and GLABRA3 (bHLH) control tomato (Solanum lycopersicum) anthocyanin biosynthesis. Anthocyanins 83-94 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 30-37 25268379-3 2014 CPC and GL3 are also known to be involved in anthocyanin biosynthesis. Anthocyanins 45-56 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 8-11 25268379-4 2014 After transformation into tomato, 35S::CPC inhibited anthocyanin accumulation, whereas GL3::GL3 enhanced anthocyanin accumulation. Anthocyanins 105-116 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 87-90 25268379-4 2014 After transformation into tomato, 35S::CPC inhibited anthocyanin accumulation, whereas GL3::GL3 enhanced anthocyanin accumulation. Anthocyanins 105-116 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 92-95 24370633-9 2014 The resulting data showed that 2,4-D, NAA and IAA control anthocyanin biosynthesis by regulating the expression of TT8, GL3 and PAP1 as well as genes in the anthocyanin biosynthetic pathway, such as DFR and ANS. Anthocyanins 58-69 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 120-123 22126737-5 2012 Transcriptional analysis showed that the red cells contain the TTG1-GL3/TT8-PAP1 regulatory complex, which controls anthocyanin biosynthesis; in contrast, the white cells and the wild-type cells lack this entire complex. Anthocyanins 116-127 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 68-71 24388610-3 2014 In Arabidopsis thaliana, GL3, a bHLH transcription factor, is important in the MBW complex regulating trichome formation as well as in the MBW complex induced by nitrogen depletion and promoting anthocyanin formation. Anthocyanins 195-206 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 25-28 23603939-0 2013 Tomato (Solanum lycopersicum) homologs of TRIPTYCHON (SlTRY) and GLABRA3 (SlGL3) are involved in anthocyanin accumulation. Anthocyanins 97-108 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 65-72 23603939-4 2013 CPC and GL3 are also known to be involved in anthocyanin biosynthesis. Anthocyanins 45-56 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 8-11 23603939-5 2013 Here, we show that anthocyanin accumulation was repressed in the CPC::SlTRY and GL3::SlGL3 transgenic plants, suggesting that SlTRY and SlGL3 can influence anthocyanin pigment synthesis. Anthocyanins 19-30 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 80-83 22644767-6 2012 Examination of the BoMYB2 transgenic lines in Arabidopsis bHLH mutant backgrounds demonstrated that TT8, EGL3, and GL3 were all involved in the BoMYB2-mediated anthocyanin biosynthesis. Anthocyanins 176-187 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 122-125 22669605-0 2012 Regulation of anthocyanin biosynthesis by nitrogen in TTG1-GL3/TT8-PAP1-programmed red cells of Arabidopsis thaliana. Anthocyanins 14-25 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 59-62 22669605-2 2012 In this investigation, we report the nitrogen regulation of anthocyanin biosynthesis activated by TTG1-GL3/TT8-PAP1 in red pap1-D cells. Anthocyanins 60-71 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 103-106 22669605-8 2012 These results show that nitrogen regulation of anthocyanin biosynthesis in red cells undergoes a mechanism by which nitrogen controls the expression of genes encoding both main components of the TTG1-GL3/TT8-PAP1 complex and negative regulators. Anthocyanins 47-58 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 200-203 21545406-5 2011 Furthermore, the expression level of JA-induced Myb/bHLH transcription factors such as PAP1, PAP2, and GL3, which are components of the WD-repeat/Myb/bHLH transcriptional complexes that mediate the "late" anthocyanin biosynthesis genes, was lower in the BR mutants than that in wild type. Anthocyanins 205-216 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 103-106 21551388-6 2011 Overexpression of the MYB transcription factor MYB75 and bHLH factors (GL3 and EGL3) restored anthocyanin accumulation and trichome initiation in the coi1 mutant, respectively. Anthocyanins 94-105 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 71-74 19621239-0 2009 The endogenous GL3, but not EGL3, gene is necessary for anthocyanin accumulation as induced by nitrogen depletion in Arabidopsis rosette stage leaves. Anthocyanins 56-67 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 15-18 21210143-8 2011 Microarray and RT-PCR analyses demonstrated that the TTG1-GL3/TT8-PAP1 complex regulated the biosynthesis of anthocyanins. Anthocyanins 109-121 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 58-61 19621239-6 2009 Hence, low expression of DFR appears to be the bottleneck preventing anthocyanin synthesis in the gl3 mutant. Anthocyanins 69-80 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 98-101 19621239-1 2009 The bHLH transcription factors EGL3 (ENHANCER OF GLABRA3) and its close homologue GL3 (GLABRA3) are important regulators of the anthocyanin pathway in Arabidopsis thaliana, and together with TTG1 (a WD40 repeat protein) and MYB transcription factors regulate specific genes in the pathway. Anthocyanins 128-139 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 32-35 19621239-1 2009 The bHLH transcription factors EGL3 (ENHANCER OF GLABRA3) and its close homologue GL3 (GLABRA3) are important regulators of the anthocyanin pathway in Arabidopsis thaliana, and together with TTG1 (a WD40 repeat protein) and MYB transcription factors regulate specific genes in the pathway. Anthocyanins 128-139 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 49-56 19621239-3 2009 In this study we show that anthocyanins accumulate in both wild type and egl3, but not in gl3 loss-of-function mutants when depleted of nitrogen. Anthocyanins 27-39 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 74-77 12917293-6 2003 The double bHLH mutant, gl3 egl3, has a pleiotropic phenotype like ttg1 having defective anthocyanin production, seed coat mucilage production, and position-dependent root hair spacing. Anthocyanins 89-100 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 24-27 19596700-7 2009 It is speculated that COI1 regulates the expression of the transcription factors, including PAP1, PAP2, and GL3, which mediates the "late" anthocyanin biosynthetic genes DFR, LDOX, and UF3GT, thereby modulating JA-induced anthocyanin biosynthesis in Arabidopsis. Anthocyanins 139-150 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 108-111 19596700-7 2009 It is speculated that COI1 regulates the expression of the transcription factors, including PAP1, PAP2, and GL3, which mediates the "late" anthocyanin biosynthetic genes DFR, LDOX, and UF3GT, thereby modulating JA-induced anthocyanin biosynthesis in Arabidopsis. Anthocyanins 222-233 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 108-111 17053893-7 2007 At least three different bHLH domain transcription factors promote anthocyanin synthesis, and transcripts for one of these, i.e. GL3 were found to be sixfold enhanced by nitrogen deficiency in rosette leaves. Anthocyanins 67-78 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 129-132 17053893-10 2007 Together with MYB factors, especially PAP2, GL3 appears to be the BHLH partner for anthocyanin accumulation in response to nitrogen deficiency. Anthocyanins 83-94 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 44-47 17766004-1 2008 In this work we analysed, at the transcript level, the response of Arabidopsis anthocyanin regulatory genes of the MYB (PAP1 and PAP2), bHLH (TT8, EGL3 and GL3) and WD40 (TTG1) families to white light in seedlings and to different light qualities in rosette leaves. Anthocyanins 79-90 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 148-151 11063707-3 2000 The complex phenotype caused by ttg1 mutations is suppressed by ectopic expression of the maize anthocyanin regulator R. Here it is demonstrated that the Arabidopsis trichome development locus GLABRA3 (GL3) encodes an R homolog. Anthocyanins 96-107 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 193-200 12956536-0 2003 Two basic-helix-loop-helix genes (MYC-146 and GL3) from Arabidopsis can activate anthocyanin biosynthesis in a white-flowered Matthiola incana mutant. Anthocyanins 81-92 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 34-49 12956536-2 2003 Two Arabidopsis bHLH genes, GLABRA3 (GL3) and MYC-146, encode proteins that are similar throughout the predicted amino acid sequence to R and DELILA, which regulate anthocyanin production in maize and snapdragon, respectively. Anthocyanins 165-176 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 28-35 12956536-2 2003 Two Arabidopsis bHLH genes, GLABRA3 (GL3) and MYC-146, encode proteins that are similar throughout the predicted amino acid sequence to R and DELILA, which regulate anthocyanin production in maize and snapdragon, respectively. Anthocyanins 165-176 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 37-40 12956536-6 2003 The lack of anthocyanin-deficient Arabidopsis mutants mapping to the locations of GL3 and MYC-146 suggests that the two bHLH proteins may be partially redundant and overlap in function. Anthocyanins 12-23 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 82-85 11063707-3 2000 The complex phenotype caused by ttg1 mutations is suppressed by ectopic expression of the maize anthocyanin regulator R. Here it is demonstrated that the Arabidopsis trichome development locus GLABRA3 (GL3) encodes an R homolog. Anthocyanins 96-107 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 202-205