PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31606569-6 2020 Dimethoate did not influence Leydig cell number but reduced Leydig cell size and down-regulated Star, Cyp11a1, and Hsd3b1 in Leydig cells as well as their protein expression. Dimethoate 0-10 steroidogenic acute regulatory protein Rattus norvegicus 96-100 31606569-10 2020 Further study demonstrated that dimethoate also down-regulated the expression of Star, Cyp11a1, and Hsd3b1 at 5 or 50 muM in vitro. Dimethoate 32-42 steroidogenic acute regulatory protein Rattus norvegicus 81-85 31606569-12 2020 In conclusion, dimethoate targets Star, Cyp11a1, and Hsd3b1 transcription, thus blocking Leydig cell differentiation during puberty. Dimethoate 15-25 steroidogenic acute regulatory protein Rattus norvegicus 34-38