PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26350273-2	2015	Hydrocodone undergoes cytochrome P-450 (CYP)-mediated metabolism involving the CYP3A4 and CYP2D6 isozymes.	Hydrocodone	0-11	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	22-38	
26350273-2	2015	Hydrocodone undergoes cytochrome P-450 (CYP)-mediated metabolism involving the CYP3A4 and CYP2D6 isozymes.	Hydrocodone	0-11	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	40-43	
21999760-5	2011	Opioids metabolized by the drug metabolizing enzymes of the cytochrome P450 (CYP450) system (codeine, oxycodone, hydrocodone, fentanyl, tramadol, and methadone) are associated with numerous DDIs that can result in either a reduction in opioid effect or excess opioid effects.	Hydrocodone	113-124	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	60-75	
21999760-5	2011	Opioids metabolized by the drug metabolizing enzymes of the cytochrome P450 (CYP450) system (codeine, oxycodone, hydrocodone, fentanyl, tramadol, and methadone) are associated with numerous DDIs that can result in either a reduction in opioid effect or excess opioid effects.	Hydrocodone	113-124	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	77-83