PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26937175-5 2016 RESULTS AND CONCLUSION: We found that the MDM2 inhibitor MI-319 induced RCC cell apoptosis mainly dependent on p53 overexpression, while the mTOR antagonist rapamycin promoted RCC cell apoptosis primarily through upregulation of HIF1alpha expression. 2-methyl-4-isothiazolin-3-one 57-59 hypoxia inducible factor 1 subunit alpha Homo sapiens 229-238