PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33878623-6 2021 Exposure of rats to AlCl3 for 20 consecutive days resulted in a significant decrease in serum and testicular superoxide dismutase and catalase activities, serum testosterone level, and sperm count and motility; on the other hand, an increase in nitric oxide, malondialdehyde, aluminum, and serum tumor necrosis factor-alpha levels. Aluminum Chloride 20-25 catalase Rattus norvegicus 134-142 34741695-6 2021 Oral administration of AlCl3 showed an oxidative damage confirmed by an increase in malondialdehyde and nitric oxide levels and superoxide dismutase activity and accompanied by a decrease in glutathione content and catalase activity. Aluminum Chloride 23-28 catalase Rattus norvegicus 215-223 35554794-10 2022 The results showed that AlCl3-intoxication causes significant impairment of memory, enhances anxiety-like behavior, acetyl cholinesterase (AChE) activity, malondialdehydes (MDA) level, and concomitant decrease in the activities of superoxide dismutase (SOD) and catalase (CAT) in the cortex and hippocampus regions of rat brain. Aluminum Chloride 24-29 catalase Rattus norvegicus 272-275 35554794-12 2022 However, co-administration of AA with AlCl3 significantly attenuated the behavioral alterations, restored SOD and CAT activities, while reduced AChE activity and MDA content. Aluminum Chloride 38-43 catalase Rattus norvegicus 114-117 35341471-8 2022 We found that chronic oral exposure of aluminum chloride causes a significant increase in structural hallmarks such as Abeta1-42 and p231-tau levels along with proinflammatory cytokines (TNF-alpha and IL-6), oxidative stress, and a decrease in antioxidant markers such as GSH and catalase. Aluminum Chloride 39-56 catalase Rattus norvegicus 280-288 28241996-3 2017 The results showed that administration of AlCl3 to rats induced significant increase (P < 0.05) in thiobarbituric acid reactive substance and decrease (P < 0.05) in glutathione, catalase, and superoxide dismutase in brain and testis homogenates. Aluminum Chloride 42-47 catalase Rattus norvegicus 184-192 33368464-6 2021 In the AlCl3 -treated group, MDA level increased and GSH level, GPx and CAT activities decreased compared with those of the control group. Aluminum Chloride 7-12 catalase Rattus norvegicus 72-75 32971212-7 2020 Moreover, AlCl3 exposure decreased the level of GABA and the activity of glutathione peroxidase (GPx), catalase (CAT) and superoxide dismutase (SOD) in the hippocampus (HP) and the frontal cortex (FC). Aluminum Chloride 10-15 catalase Rattus norvegicus 103-111 32971212-7 2020 Moreover, AlCl3 exposure decreased the level of GABA and the activity of glutathione peroxidase (GPx), catalase (CAT) and superoxide dismutase (SOD) in the hippocampus (HP) and the frontal cortex (FC). Aluminum Chloride 10-15 catalase Rattus norvegicus 113-116 32932753-4 2020 Biochemically, AlCl3 administration resulted in marked elevation in levels of lipid peroxidation (LPO) and nitric oxide (NO) and decrease in levels of reduced glutathione (GSH), catalase (CAT), and superoxide dismutase (SOD). Aluminum Chloride 15-20 catalase Rattus norvegicus 178-186 32932753-4 2020 Biochemically, AlCl3 administration resulted in marked elevation in levels of lipid peroxidation (LPO) and nitric oxide (NO) and decrease in levels of reduced glutathione (GSH), catalase (CAT), and superoxide dismutase (SOD). Aluminum Chloride 15-20 catalase Rattus norvegicus 188-191 30771656-5 2019 Secondly, MT attenuated the AlCl3-induced oxidative stress in rat spleen by decreasing the levels of ROS and MDA, while increasing the activities of SOD and CAT. Aluminum Chloride 28-33 catalase Rattus norvegicus 157-160 30771656-7 2019 Finally, MT increased Nrf2 nuclear translocation, and Nrf2 target genes (HO-1, NQO1, SOD1 and CAT) mRNA expressions in the spleen of AlCl3-exposed rat. Aluminum Chloride 133-138 catalase Rattus norvegicus 94-97 26354416-7 2016 The results showed that AlCl3 elevated the systolic and mean arterial blood pressure of rats, increased the osmotic fragility, decreased the percentage of membrane protein, inhibited the activities of Na(+)/K(+)-ATPase, Mg(2+)-ATPase, Ca(2+)-ATPase, CAT, SOD and GSH-pX, and increased the MDA content of erythrocyte membrane. Aluminum Chloride 24-29 catalase Rattus norvegicus 250-253 26307418-10 2015 Our findings showed that in rats co-administered AlCl(3) and STZ (AD + DM rats), prefrontal levels of GSH reduced significantly (p < 0.05), while reductions in SOD and CAT were not significant (p > 0.05) compared with the controls. Aluminum Chloride 49-56 catalase Rattus norvegicus 168-171 25253934-5 2014 RESULTS: Subacute exposure to AlCl3(5 mg/kg) led to significant decrease in levels of GSH, vitamin E and activities of SOD, CAT, GPx, and an increase in LPO of cerebral cortex. Aluminum Chloride 30-35 catalase Rattus norvegicus 124-127 25613582-13 2015 Biochemical analysis of the brain revealed that chronic administration of AlCl3 significantly increased lipid peroxidation and decreased levels of acetyl cholinesterase, catalase, reduced glutathione and glutathione reductase, an index of oxidative stress process. Aluminum Chloride 74-79 catalase Rattus norvegicus 170-178 22001979-7 2011 Aluminium chloride (100 mg/kg) was administered daily for six weeks that significantly increased cognitive dysfunction in the Morris water maze and oxidative damage as indicated by a rise in lipid peroxidation and nitrite concentration and depleted reduced glutathione, superoxide dismutase, catalase and glutathione S-transferase activity compared to sham treatment. Aluminum Chloride 0-18 catalase Rattus norvegicus 292-300 19425234-9 2009 AlCl3 caused a decrease in testes, seminal vesicle and epididymis weights, sperm concentration, motility, testosterone level and the activities of 17-ketosteroid reductase, CAT and GST, and GSH content. Aluminum Chloride 0-5 catalase Rattus norvegicus 173-176