PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22165673-8	2011	Brain TAC, Bcl-2, BDNF and Ach levels were decreased significantly as a result of AlCl3 supplementation to ovariectomized rats.	Aluminum Chloride	82-87	BCL2, apoptosis regulator	Rattus norvegicus	11-16	
33368464-9	2021	It was determined that Caspase-3 expression decreased, and Bcl-2 expression increased in AlCl3  + ESC group compared to AlCl3 group.	Aluminum Chloride	89-94	BCL2, apoptosis regulator	Rattus norvegicus	59-64	
32950828-5	2020	Real time-PCR and western blot suggested that rutin, puerarin and 100 mg/(kg bw)/day silymarin could decrease the AlCl3-induced high expression of Bcl-2 associated X protein (Bax) mRNA and protein in hippocampus, but the expression of B cell lymphoma/leukemia-2 (Bcl-2) mRNA and protein was not significantly different among groups.	Aluminum Chloride	114-119	BCL2, apoptosis regulator	Rattus norvegicus	235-261	
32950828-5	2020	Real time-PCR and western blot suggested that rutin, puerarin and 100 mg/(kg bw)/day silymarin could decrease the AlCl3-induced high expression of Bcl-2 associated X protein (Bax) mRNA and protein in hippocampus, but the expression of B cell lymphoma/leukemia-2 (Bcl-2) mRNA and protein was not significantly different among groups.	Aluminum Chloride	114-119	BCL2, apoptosis regulator	Rattus norvegicus	147-152	
33133350-8	2020	MEL also suppressed the apoptotic effect of AlCl3 by enhancing Bcl-2 protein expression in the liver and kidney and decreasing the expression levels of proinflammatory cytokines.	Aluminum Chloride	44-49	BCL2, apoptosis regulator	Rattus norvegicus	63-68	
32089784-9	2020	Exposure to AlCl3 resulted in a significant (p < 0.01) elevation in the levels of nitric oxide and 8-hydroxy-2-deoxyguanosine (8-OHdG), enhanced the activity of caspase-3, increased the level of proapoptotic protein Bax and reduced the levels of antiapoptotic protein Bcl-2, and significantly (p < 0.01) reduced the levels of SOD and GPx.	Aluminum Chloride	12-17	BCL2, apoptosis regulator	Rattus norvegicus	271-276	
30771656-6	2019	Thirdly, MT relieved the AlCl3-induced apoptosis in rat spleen by increasing the MMP and Bcl-2 mRNA and protein expressions, while decreasing apoptosis rates, activity of Caspase-3 and pro-apoptotic gene expression.	Aluminum Chloride	25-30	BCL2, apoptosis regulator	Rattus norvegicus	89-94	
29027106-7	2018	Furthermore, AlCl3 exposure inhibited Bcl-2 protein expression and increased the expressions of Bax, Bak, and Bim in varying degrees.	Aluminum Chloride	13-18	BCL2, apoptosis regulator	Rattus norvegicus	38-43	
26896572-8	2016	d-gal and AlCl3-treated caused a decline in spatial learning and memory, hippocampal histopathological abnormalities and increased Abeta1-40 levels in the brain cortex and hippocampus along with decreased Bcl-2 and ChAT expression in the hippocampus.	Aluminum Chloride	10-15	BCL2, apoptosis regulator	Rattus norvegicus	205-210	
29704576-9	2018	In addition, AlCl3 caused oxidative stress, up-regulated expression of c-Jun and pro-apoptotic factors with increased p-JNK/JNK ratio and down-regulated expression of anti-apoptotic factor Bcl-2 in bone.	Aluminum Chloride	13-18	BCL2, apoptosis regulator	Rattus norvegicus	189-194	
27476752-4	2016	The results showed that in the AlCl3-treated rats serum CRH, ACTH and GCs contents, lymphocyte GC receptors (GCR) mRNA and nuclear protein expressions, caspase 3 and 9 mRNA expressions and activities increased, while Bcl-2/Bax ratio and NF-kappaB mRNA and nuclear protein expressions decreased compared with the CG.	Aluminum Chloride	31-36	BCL2, apoptosis regulator	Rattus norvegicus	217-222	
25578489-5	2015	The results showed that the serum TBA concentration, the early and total hepatocyte apoptosis indexes, and protein and mRNA expression of Bax increased, while protein and mRNA expression of Bcl-2 decreased in AlCl3-treated rats.	Aluminum Chloride	209-214	BCL2, apoptosis regulator	Rattus norvegicus	190-195