PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29294264-3 2017 Phospholipases A2 (PLA2) hydrolyze membrane glycerophospholipids at sn-2 position releasing lysophospholipid and free fatty acid. Glycerophospholipids 44-64 phospholipase A2 group IIA Homo sapiens 0-17 29294264-3 2017 Phospholipases A2 (PLA2) hydrolyze membrane glycerophospholipids at sn-2 position releasing lysophospholipid and free fatty acid. Glycerophospholipids 44-64 phospholipase A2 group IIA Homo sapiens 19-23 18405237-1 2008 Phospholipases A(2) (PLA2s) are esterases that hydrolyze the sn-2 ester of glycerophospholipids and constitute one of the largest families of lipid hydrolyzing enzymes. Glycerophospholipids 75-95 phospholipase A2 group IIA Homo sapiens 21-26 20153800-1 2010 Phospholipases A2 (PLA2) are a family of enzymes that catalyze the hydrolysis of the sn-2 ester bond of glycerophospholipids liberating lysophospholipids and free fatty acids; important second messengers involved in atherogenesis. Glycerophospholipids 104-124 phospholipase A2 group IIA Homo sapiens 19-23 17827229-2 2008 We explored what type of side group (small versus bulky groups, hydrophobic versus polar groups) can be introduced at the sn-1 position of the glycerol backbone of glycerophospholipids and at the same time be hydrolyzed by sPLA(2). Glycerophospholipids 164-184 phospholipase A2 group IIA Homo sapiens 223-229 24939539-1 2014 Phospholipases A2 (PLA2) belong to a superfamily of enzymes that catalyze the hydrolysis of glycerophospholipids at the sn-2 position, producing nonesterified fatty acids and lysophospholipids. Glycerophospholipids 92-112 phospholipase A2 group IIA Homo sapiens 19-23 23698096-3 2013 Asymmetry and diversity of membrane glycerophospholipids are generated in the remodelling pathway (Lands" cycle), which are conducted by the concerted actions of phospholipases A2 (PLA2s) and lysophospholipid acyltransferases (LPLATs). Glycerophospholipids 36-56 phospholipase A2 group IIA Homo sapiens 181-186 20127525-1 2010 Phospholipases A(2) (PLA(2)s) are a diverse family of lipolytic enzymes which hydrolyze the acyl bond at the sn-2 position of glycerophospholipids to produce free fatty acids and lysophospholipids. Glycerophospholipids 126-146 phospholipase A2 group IIA Homo sapiens 21-28 17197234-6 2007 Surprisingly, the group IIA sPLA(2) hydrolysis remained minimal at 10-15% for all minor glycerophospholipids, and was of the order seen for the PtdCho hydrolysis by group IIA sPLA(2) at the 4-h digestion time. Glycerophospholipids 88-108 phospholipase A2 group IIA Homo sapiens 28-34 12573364-5 2002 sPLA(2) is calcium-dependent and hydrolyses the sn-2 acyl group of glycerophospholipids of lipoproteins and cell membranes to produce lyso-PC and free fatty acids. Glycerophospholipids 67-87 phospholipase A2 group IIA Homo sapiens 0-7 12531539-1 2002 Phospolipase A(2) (PLA(2)) is the esterase activity that cleaves the sn-2 ester bond in glycerophospholipids, releasing free fatty acids and lysophospholipids. Glycerophospholipids 88-108 phospholipase A2 group IIA Homo sapiens 0-17 12531539-1 2002 Phospolipase A(2) (PLA(2)) is the esterase activity that cleaves the sn-2 ester bond in glycerophospholipids, releasing free fatty acids and lysophospholipids. Glycerophospholipids 88-108 phospholipase A2 group IIA Homo sapiens 19-25 14726513-7 2004 The viral PLA(2)s did not display a preference for unsaturated versus saturated sn-2 fatty acyl chains and hydrolyzed all major classes of glycero-phospholipids except phosphatidylinositol. Glycerophospholipids 139-160 phospholipase A2 group IIA Homo sapiens 10-17 8869442-1 1996 Group II phospholipase A2 (membrane-associated phospholipase A2, M-PLA2) hydrolyses the 2-acyl position of a glycerophospholipid. Glycerophospholipids 109-128 phospholipase A2 group IIA Homo sapiens 67-71 11080677-4 2000 All of these sPLA(2)s catalyze the hydrolysis of glycerophospholipids at the sn-2 position to release free fatty acids and lysophospholipids, and thus could be important for the biosynthesis of biologically active lipid mediators. Glycerophospholipids 49-69 phospholipase A2 group IIA Homo sapiens 13-19 10322502-1 1999 Phospholipases A2 (PLA2s) are enzymes that catalyse the hydrolysis of the sn-2 acyl bond of glycerophospholipids to produce free fatty acids and lysophospholipids. Glycerophospholipids 92-112 phospholipase A2 group IIA Homo sapiens 19-24 9799801-8 1998 Group IIA phospholipase A2 preferentially attacked the hydroxy and hydroperoxy linoleates and possibly other oxygenated fatty acids, which were released from the glycerophospholipids at early times of incubation. Glycerophospholipids 162-182 phospholipase A2 group IIA Homo sapiens 0-26 9481780-2 1998 The aims of this brief commentary are: (1) to review recent data concerning the expression of secretory PLA2 isozymes in human gestational tissues; and (2) to present a case for their involvement in regulating the expression of glycerophospholipids in the exoplasmic monolayer of the cell membrane. Glycerophospholipids 228-248 phospholipase A2 group IIA Homo sapiens 104-108 9481783-1 1998 Recently, a model has been proposed for the involvement of secretory phospholipase A2 (sPLA2) in the onset of and/or progression of human labour via the metabolism of cell membrane glycerophospholipids to generate biologically active, phospholipid-derived mediators. Glycerophospholipids 181-201 phospholipase A2 group IIA Homo sapiens 59-85 9481783-1 1998 Recently, a model has been proposed for the involvement of secretory phospholipase A2 (sPLA2) in the onset of and/or progression of human labour via the metabolism of cell membrane glycerophospholipids to generate biologically active, phospholipid-derived mediators. Glycerophospholipids 181-201 phospholipase A2 group IIA Homo sapiens 87-92 11469536-2 2001 Secretory type IIA PLA2 (sPLA2-IIA), which hydrolyzes fatty acids bound at the sn-2 position of glycerophospholipids, has been detected universally in a variety of mammalian tissues and cells. Glycerophospholipids 96-116 phospholipase A2 group IIA Homo sapiens 19-23 11162354-2 2001 Type II phospholipase A(2)(PLA2) hydrolyses glycerophospholipids, releasing free fatty acid for conversion into potent biological mediators, such as prostaglandins, which play a significant role in both the onset and progression of human labour and the activation of inflammatory reactions. Glycerophospholipids 44-64 phospholipase A2 group IIA Homo sapiens 27-31 8934451-3 1996 Sterols structurally related to cholesterol and some steryl esters inhibited the activity of L. giganteum phospholipase A2 (PLA2), an enzyme that hydrolyzes fatty acids from the sn-2 position of glycerophospholipids. Glycerophospholipids 195-215 phospholipase A2 group IIA Homo sapiens 124-128 8872534-1 1996 Phospholipases A2 (PLA2s) catalyze the hydrolysis of glycerophospholipids at the sn-2 position, and their inhibition is considered a rational approach for the prevention and treatment of inflammation. Glycerophospholipids 53-73 phospholipase A2 group IIA Homo sapiens 19-24 8198986-1 1994 Membrane-associated phospholipase A2 (M-PLA2) is an enzyme that hydrolyses the sn-2 fatty acyl ester bond of phosphoglycerides. Glycerophospholipids 109-126 phospholipase A2 group IIA Homo sapiens 40-44 23214144-1 2012 Phospholipase A2 (EC 3.1.1.4, PLA2) belongs to the group of enzymes that catalyze the hydrolysis of the ester bond at position sn-2 of glycerophospholipids and hence generate free fatty acids including arachidonic acid. Glycerophospholipids 135-155 phospholipase A2 group IIA Homo sapiens 30-34 34478892-4 2021 Herein, we review the existing literature about the implications of phospholipases 2 (PLA2s), a large family of enzymes that catalyze the hydrolysis of fatty acids at the sn-2 position of glycerophospholipids, in ARDS-related pathology. Glycerophospholipids 188-208 phospholipase A2 group IIA Homo sapiens 86-91 7722506-1 1995 Phospholipases A2 (PLA2) are a family of enzymes that catalyze the removal of fatty acid residues from phosphoglycerides. Glycerophospholipids 103-120 phospholipase A2 group IIA Homo sapiens 19-23