PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8830310-3 1995 We report here that AChE binds A beta nac and accelerates amyloid formation by the same peptide. nac 38-41 acetylcholinesterase (Cartwright blood group) Homo sapiens 20-24 8830310-4 1995 No such effect was observed with A beta ac, the amyloidogenic conformer, suggesting that AChE acts as a "pathological chaperone" inducing a conformational transition from A beta nac into A beta ac in vitro. nac 178-181 acetylcholinesterase (Cartwright blood group) Homo sapiens 89-93 35489467-6 2022 Among those oximes, trimedoxime seems to be the most promising, since it showed lower values of energy in the MM-PBSA calculations, a higher stability inside the catalytic anionic center (CAS) of HssAChE, and was able to adopt a position closer to the NAC that could enable the reactivation mechanism. nac 252-255 acetylcholinesterase (Cartwright blood group) Homo sapiens 196-203