PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16783693-0 2006 Reduction of cytotoxicity of the alkaloid emetine through P-glycoprotein (MDR1/ABCB1) in human Caco-2 cells and leukemia cell lines. Emetine 42-49 ATP binding cassette subfamily B member 1 Homo sapiens 58-72 16783693-0 2006 Reduction of cytotoxicity of the alkaloid emetine through P-glycoprotein (MDR1/ABCB1) in human Caco-2 cells and leukemia cell lines. Emetine 42-49 ATP binding cassette subfamily B member 1 Homo sapiens 74-78 16783693-0 2006 Reduction of cytotoxicity of the alkaloid emetine through P-glycoprotein (MDR1/ABCB1) in human Caco-2 cells and leukemia cell lines. Emetine 42-49 ATP binding cassette subfamily B member 1 Homo sapiens 79-84 16783693-1 2006 The cytotoxicity of the alkaloid emetine was determined in six human cell lines that differ in the expression of ABC transporters, such as multiple drug resistance protein 1 (MDR1/ABCB1) and multidrug resistance associated protein 1 (MRP1/ABCC1). Emetine 33-40 ATP binding cassette subfamily B member 1 Homo sapiens 175-179 16783693-1 2006 The cytotoxicity of the alkaloid emetine was determined in six human cell lines that differ in the expression of ABC transporters, such as multiple drug resistance protein 1 (MDR1/ABCB1) and multidrug resistance associated protein 1 (MRP1/ABCC1). Emetine 33-40 ATP binding cassette subfamily B member 1 Homo sapiens 180-185 16783693-2 2006 Emetine reveals a substantial cytotoxicity due to apoptosis that is inversely correlated with the expression of MDR1. Emetine 0-7 ATP binding cassette subfamily B member 1 Homo sapiens 112-116 16783693-4 2006 Apparently emetine is a substrate for MDR1 but not for MRP1. Emetine 11-18 ATP binding cassette subfamily B member 1 Homo sapiens 38-42 16783693-5 2006 Furthermore, emetine is able to up-regulate the expression of MDR1 as shown IN VITRO by real-time PCR and transport activity studies. Emetine 13-20 ATP binding cassette subfamily B member 1 Homo sapiens 62-66 1359408-1 1992 Two P-glycoprotein genes (EhPgp1 and EhPgp2) from the protozoan parasite Entamoeba histolytica were sequenced from a genomic library made with the DNA of an emetine-resistant ameba mutant, which overexpresses mRNAs homologous to segments of the human mdr1 (P-glycoprotein) gene. Emetine 157-164 ATP binding cassette subfamily B member 1 Homo sapiens 4-18 1364101-1 1992 Six different P-glycoprotein gene segments were identified from an emetine-resistant E. histolytica mutant, which overexpresses mRNAs homologous to segments of the human mdr1 (P-glycoprotein) gene. Emetine 67-74 ATP binding cassette subfamily B member 1 Homo sapiens 14-28 1364101-1 1992 Six different P-glycoprotein gene segments were identified from an emetine-resistant E. histolytica mutant, which overexpresses mRNAs homologous to segments of the human mdr1 (P-glycoprotein) gene. Emetine 67-74 ATP binding cassette subfamily B member 1 Homo sapiens 170-174 1364101-1 1992 Six different P-glycoprotein gene segments were identified from an emetine-resistant E. histolytica mutant, which overexpresses mRNAs homologous to segments of the human mdr1 (P-glycoprotein) gene. Emetine 67-74 ATP binding cassette subfamily B member 1 Homo sapiens 176-190