PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9804860-1 1998 The equilibrative nucleoside transporters (ENTs) are a newly recognized family of membrane proteins of which hENT1 is the nitrobenzylmercaptopurine ribonucleoside (NBMPR)-sensitive (es) and hENT2 the NBMPR-insensitive (ei) transporter of human cells. Nitrobenzylmercaptopurine Ribonucleoside 122-162 solute carrier family 29 member 1 (Augustine blood group) Homo sapiens 109-114 27995448-6 2017 Adenosine uptake by hENT1 is competitively inhibited by nitrobenzylmercaptopurine ribonucleoside (NBMPR), nucleosides, deoxynucleosides, and nucleoside-derived anti-cancer and anti-viral drugs. Nitrobenzylmercaptopurine Ribonucleoside 56-96 solute carrier family 29 member 1 (Augustine blood group) Homo sapiens 20-25 21795683-2 2011 Both transport purine and pyrimidine nucleosides and are distinguished functionally by a difference in sensitivity to inhibition by nanomolar concentrations of nitrobenzylmercaptopurine ribonucleoside (NBMPR), hENT1 being NBMPR-sensitive. Nitrobenzylmercaptopurine Ribonucleoside 160-200 solute carrier family 29 member 1 (Augustine blood group) Homo sapiens 210-215 19788890-3 2010 Capan-2 cells displayed the lowest levels of (1) extracellular nitrobenzylmercaptopurine ribonucleoside (NBMPR) binding, which represents cell-surface hENT1, (2) FLT and gemcitabine uptake during short (1-45s) and prolonged (1h) periods, and (3) gemcitabine sensitivity. Nitrobenzylmercaptopurine Ribonucleoside 63-103 solute carrier family 29 member 1 (Augustine blood group) Homo sapiens 151-156 18669604-6 2008 [(3)H]FLT uptake in MCF-7, A549, U251, A498, MIA PaCa-2, and Capan-2 cells was inhibited at least 50% by the hENT1 inhibitor nitrobenzylmercaptopurine ribonucleoside (NBMPR). Nitrobenzylmercaptopurine Ribonucleoside 125-165 solute carrier family 29 member 1 (Augustine blood group) Homo sapiens 109-114 18462193-1 2008 hENT1 (human equilibrative nucleoside transporter 1) is inhibited by nanomolar concentrations of various structurally distinct coronary vasodilator drugs, including dipyridamole, dilazep, draflazine, soluflazine and NBMPR (nitrobenzylmercaptopurine ribonucleoside). Nitrobenzylmercaptopurine Ribonucleoside 223-263 solute carrier family 29 member 1 (Augustine blood group) Homo sapiens 0-5 18462193-1 2008 hENT1 (human equilibrative nucleoside transporter 1) is inhibited by nanomolar concentrations of various structurally distinct coronary vasodilator drugs, including dipyridamole, dilazep, draflazine, soluflazine and NBMPR (nitrobenzylmercaptopurine ribonucleoside). Nitrobenzylmercaptopurine Ribonucleoside 223-263 solute carrier family 29 member 1 (Augustine blood group) Homo sapiens 13-51 17379602-2 2007 Human equilibrative nucleoside transporter 1 (hENT1) is inhibited by nanomolar concentrations of structurally diverse compounds, including dipyridamole, dilazep, nitrobenzylmercaptopurine ribonucleoside (NBMPR), draflazine, and soluflazine. Nitrobenzylmercaptopurine Ribonucleoside 162-202 solute carrier family 29 member 1 (Augustine blood group) Homo sapiens 6-44 17379602-2 2007 Human equilibrative nucleoside transporter 1 (hENT1) is inhibited by nanomolar concentrations of structurally diverse compounds, including dipyridamole, dilazep, nitrobenzylmercaptopurine ribonucleoside (NBMPR), draflazine, and soluflazine. Nitrobenzylmercaptopurine Ribonucleoside 162-202 solute carrier family 29 member 1 (Augustine blood group) Homo sapiens 46-51 15905191-5 2005 Inhibition of SLC29A1 by nitrobenzylmercaptopurine ribonucleoside (NBMPR) caused a 33% to 45% reduction of TGN in ALL cells in vitro (P < .006), consistent with the gene expression findings. Nitrobenzylmercaptopurine Ribonucleoside 25-65 solute carrier family 29 member 1 (Augustine blood group) Homo sapiens 14-21 15486050-7 2005 Exposure to nitrobenzylmercaptopurine ribonucleoside conferred resistance to BR and TR cytotoxicity to hENT1-containing CEM cells, thereby demonstrating the importance of transport capacity for manifestation of cytoxicity. Nitrobenzylmercaptopurine Ribonucleoside 12-52 solute carrier family 29 member 1 (Augustine blood group) Homo sapiens 103-108 15471562-4 2004 In a highly gemcitabine-sensitive cell line, NCI-H23, the sensitivity to gemcitabine was inhibited by nitrobenzylmercaptopurine ribonucleoside (NBMPR), an inhibitor of hENT1, without significant modulation of hENT1 expression. Nitrobenzylmercaptopurine Ribonucleoside 102-142 solute carrier family 29 member 1 (Augustine blood group) Homo sapiens 168-173 15205344-6 2004 Application of an inhibitor of SLC29A1, nitrobenzylmercaptopurine ribonucleoside, significantly reduced the potency of these two drugs, indicating that SLC29A1 plays a role in cellular uptake. Nitrobenzylmercaptopurine Ribonucleoside 40-80 solute carrier family 29 member 1 (Augustine blood group) Homo sapiens 31-38 15205344-6 2004 Application of an inhibitor of SLC29A1, nitrobenzylmercaptopurine ribonucleoside, significantly reduced the potency of these two drugs, indicating that SLC29A1 plays a role in cellular uptake. Nitrobenzylmercaptopurine Ribonucleoside 40-80 solute carrier family 29 member 1 (Augustine blood group) Homo sapiens 152-159 12820662-5 2003 Whole-cell current measurements showed that application of extracellular nitrobenzylmercaptopurine ribonucleoside (NBMPR), a selective inhibitor of hENT1-mediated transport, had similar effects on whole-cell currents as the application of exogenous adenosine. Nitrobenzylmercaptopurine Ribonucleoside 73-113 solute carrier family 29 member 1 (Augustine blood group) Homo sapiens 148-153