PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17260960-8 2007 Using this method, it could be demonstrated that in the presence of HA-PLTP, but not LA-PLTP, [14C]DPPC was transferred from small unilamellar vesicles (SUV) to acceptor HDL3 molecules. Carbon-14 95-98 HDL3 Homo sapiens 170-174 7583579-3 1995 In [14C]lyso-PC-labeled or [14C]choline (Cho)-labeled cells, a biphasic activation of PC-specific phospholipase D (PLD) with peak maxima 30 to 60 seconds and 5 to 7 minutes after stimulation with 20 micrograms/mL HDL3 was shown by (1) a 1.5- to 3-fold increase in Cho release, and (3) transphosphatidylation of PC to phosphatidylbutanol in the presence of 0.3% butanol. Carbon-14 4-7 HDL3 Homo sapiens 213-217 9576851-3 1998 During the current study, human apolipoprotein (apo)E-free HDL subclass 3 (HDL3) labelled with [14C]alphaTocH was used to investigate uptake mechanisms of HDL3-associated alphaTocH by a permanent hepatoblastoma cell line (HepG2). Carbon-14 96-99 HDL3 Homo sapiens 75-79 9576851-6 1998 Time-dependent studies with [14C]alphaTocH-labelled HDL3 revealed tracer uptake in 80-fold excess of apoA-I and in 4-fold excess of cholesteryl linoleate. Carbon-14 29-32 HDL3 Homo sapiens 52-56 9500707-9 1998 Concomitant with the defective HDL2- and HDL3-[14C] cholesterol translocation into bile of EFA-deficient rats, increased hepatic very-low-density lipoprotein (VLDL)-[14C] cholesterol secretion was observed in vivo. Carbon-14 47-50 HDL3 Homo sapiens 41-45 10082958-4 1999 In the case of VLDL labeled with human [14C]apoCIII1, a large fraction of the apoCIII1 transfers to HDL3 within 1 minute of mixing the two lipoproteins at either 4 degrees or 37 degrees C. As the diameter of the VLDL donor particles is decreased from 42-59 to 23-25 nm, the size of this rapidly transferring apoCIII1 pool increases from about 50% to 85%. Carbon-14 40-43 HDL3 Homo sapiens 100-104 7749882-4 1995 When cellular cholesterol was labeled to equilibrium by [14C]cholesterol incubation for 48 hours at 37 degrees C, HDL3-mediated cholesterol efflux from Tangier fibroblasts was only 50% of control fibroblasts. Carbon-14 57-60 HDL3 Homo sapiens 114-118 8462621-9 1993 Stepwise multiple-regression analysis confirmed the association of [14C] cholesterol uptake with plasma HDL3 concentrations (beta, 0.61; P = 0.004). Carbon-14 68-71 HDL3 Homo sapiens 104-108 8243874-7 1993 The addition of HDL3 (50 micrograms) resulted in a significant decrease in 14C-labelled cholesterol ester, reflecting a decrease in intracellular unesterified cholesterol, which was partially reversed by the addition of insulin. Carbon-14 75-78 HDL3 Homo sapiens 16-20 7999122-2 1994 Since this phenotype may in part be caused by a defect in the pathway mediating cholesterol efflux from peripheral cells, we investigated the HDL3-mediated mobilization of cholesterol synthesized de novo from [14C]-mevalonolactone in cultivated fibroblasts from two patients with Tangier disease. Carbon-14 210-213 HDL3 Homo sapiens 142-146 7999122-3 1994 Our results indicate that the HDL3-induced translocation of [14C]-cholesterol from intracellular pools to the plasma membrane and its subsequent secretion into the extracellular medium was approximately 50% less in the cells from the patients than in controls. Carbon-14 61-64 HDL3 Homo sapiens 30-34 8379932-6 1993 The same degree of preferential uptake of oxidized CE was observed when HDL3 was used that was doubly labelled with [3H]Ch18:2-OOH and cholesteryl [14C]oleate ([14C]Ch18:1). Carbon-14 148-151 HDL3 Homo sapiens 72-76 8379932-6 1993 The same degree of preferential uptake of oxidized CE was observed when HDL3 was used that was doubly labelled with [3H]Ch18:2-OOH and cholesteryl [14C]oleate ([14C]Ch18:1). Carbon-14 161-164 HDL3 Homo sapiens 72-76 7104306-2 1982 Initially, [14C]cholesterol was present in the donor lipoprotein particle which was either HDL2, HDL3, or LDL. Carbon-14 12-15 HDL3 Homo sapiens 97-101 2322573-6 1990 (A) During incubations, unesterified [14C]cholesterol from HDL3 readily appeared in hepatocytes. Carbon-14 38-41 HDL3 Homo sapiens 59-63 2322573-9 1990 A prior phospholipase treatment of HDL3 stimulated by 2-5-fold the uptake of [3H]cholesteryl ether, whereas the transfer of free [14C]cholesterol was minimally increased. Carbon-14 130-133 HDL3 Homo sapiens 35-39 2322573-10 1990 The uptake of 3H/14C-labelled sterols from HDL2 was 2-3-times higher than from HDL3. Carbon-14 17-20 HDL3 Homo sapiens 79-83