PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28846937-0 2017 A Novel IMP1 Inhibitor, BTYNB, Targets c-Myc and Inhibits Melanoma and Ovarian Cancer Cell Proliferation. BTYNB 24-29 MYC proto-oncogene, bHLH transcription factor Homo sapiens 39-44 28846937-5 2017 The small molecule, BTYNB, was identified as a potent and selective inhibitor of IMP1 binding to c-Myc mRNA. BTYNB 20-25 MYC proto-oncogene, bHLH transcription factor Homo sapiens 97-102 28846937-7 2017 BTYNB destabilizes c-Myc mRNA, resulting in downregulation of c-Myc mRNA and protein. BTYNB 0-5 MYC proto-oncogene, bHLH transcription factor Homo sapiens 19-24 28846937-7 2017 BTYNB destabilizes c-Myc mRNA, resulting in downregulation of c-Myc mRNA and protein. BTYNB 0-5 MYC proto-oncogene, bHLH transcription factor Homo sapiens 62-67 28846937-13 2017 With its ability to target c-Myc and to inhibit proliferation of difficult-to-target melanomas and ovarian cancer cells, and with its unique mode of action, BTYNB is a promising small molecule for further therapeutic evaluation and mechanistic studies. BTYNB 157-162 MYC proto-oncogene, bHLH transcription factor Homo sapiens 27-32