PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16280284-0	2005	Blockade of sympathetic nervous system activity by rilmenidine increases plasma adiponectin concentration in patients with essential hypertension.	Rilmenidine	51-62	adiponectin, C1Q and collagen domain containing	Homo sapiens	80-91	
16280284-4	2005	The aim of the study was to evaluate the effect of 6 months of antihypertensive therapy with rilmenidine on plasma adiponectin concentration in patients with essential hypertension.	Rilmenidine	93-104	adiponectin, C1Q and collagen domain containing	Homo sapiens	115-126	
16280284-7	2005	However after 6 months of treatment with rilmenidine a significant increase in plasma adiponectin concentration (from 12.5 +/- 6.1 to 16.9 +/- 11.1; P = .0002) was observed.	Rilmenidine	41-52	adiponectin, C1Q and collagen domain containing	Homo sapiens	86-97	
16280284-8	2005	CONCLUSIONS: Antihypertensive therapy with rilmenidine correlates with an increase of plasma adiponectin concentration without any significant changes of insulin sensitivity and body fat content in patients with essential hypertension.	Rilmenidine	43-54	adiponectin, C1Q and collagen domain containing	Homo sapiens	93-104