PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30121001-2 2018 The 2-amino-4H-pyran bearing nitro groups on both the aryl rings showed the highest activity, with an IC50 of 1.98 +- 0.09 microM against acetylcholinesterase (AChE) and 10.62 +- 0.21 microM against butyrylcholinesterase (BChE), the inhibition mechanisms on AChE and BChE receptors were revealed by means of molecular docking simulations. 2-amino-4h-pyran 4-20 acetylcholinesterase (Cartwright blood group) Homo sapiens 138-158 30121001-2 2018 The 2-amino-4H-pyran bearing nitro groups on both the aryl rings showed the highest activity, with an IC50 of 1.98 +- 0.09 microM against acetylcholinesterase (AChE) and 10.62 +- 0.21 microM against butyrylcholinesterase (BChE), the inhibition mechanisms on AChE and BChE receptors were revealed by means of molecular docking simulations. 2-amino-4h-pyran 4-20 acetylcholinesterase (Cartwright blood group) Homo sapiens 160-164 30121001-2 2018 The 2-amino-4H-pyran bearing nitro groups on both the aryl rings showed the highest activity, with an IC50 of 1.98 +- 0.09 microM against acetylcholinesterase (AChE) and 10.62 +- 0.21 microM against butyrylcholinesterase (BChE), the inhibition mechanisms on AChE and BChE receptors were revealed by means of molecular docking simulations. 2-amino-4h-pyran 4-20 acetylcholinesterase (Cartwright blood group) Homo sapiens 258-262