PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29332582-3	2017	Applying a ligand-based approach, the triazinone core emerged as a suitable scaffold to simultaneously bind the aspartic dyad of BACE-1 and the ATP site of GSK-3beta, leading to a series of small molecules endowed with a balanced micromolar affinity and a promising pharmacokinetic profile.	triazinone	38-48	beta-secretase 1	Homo sapiens	129-135	
28950235-4	2017	Recent studies revealed that only two scaffolds i.e. triazinone and curcumin act as a dual inhibitor against BACE-1 and GSK-3beta.	triazinone	53-63	beta-secretase 1	Homo sapiens	109-115	
28741112-4	2017	Docking, molecular dynamics, clustering, binding energy, and network analysis of triazinone derivatives with BACE-1 and GSK-3beta was performed to get molecular insight into the first reported dual inhibitor.	triazinone	81-91	beta-secretase 1	Homo sapiens	109-115	
29310523-3	2019	Till now only two scaffolds (triazinone and curcumin) derivatives have been reported as BACE-1 and GSK-3beta dual inhibitors.	triazinone	29-39	beta-secretase 1	Homo sapiens	88-94	
28741112-3	2017	Until now, only two-scaffold triazinone and curcumin have been reported as BACE-1 and GSK-3beta dual inhibitors.	triazinone	29-39	beta-secretase 1	Homo sapiens	75-81