PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24863930-6 2014 Furthermore, a large conductance nonspecific cation channel, which was identified previously in the vesicle membrane and has biophysical properties similar to that of an RyR, is pharmacologically affected in a manner characteristic of an RyR: it is activated in the presence of the RyR agonist ryanodine (at low concentrations) and blocked by the RyR antagonist ruthenium red. Ruthenium Red 362-375 ryanodine receptor 1, skeletal muscle Mus musculus 170-173 24863930-6 2014 Furthermore, a large conductance nonspecific cation channel, which was identified previously in the vesicle membrane and has biophysical properties similar to that of an RyR, is pharmacologically affected in a manner characteristic of an RyR: it is activated in the presence of the RyR agonist ryanodine (at low concentrations) and blocked by the RyR antagonist ruthenium red. Ruthenium Red 362-375 ryanodine receptor 1, skeletal muscle Mus musculus 238-241 9611131-3 1998 cADPR (10 nM-10 microM) induced a dose-dependent increase in [Ca2+]i, which was blocked by the cADPR receptor antagonist 8-amino-cADPR (20 microM) and by the RyR blockers ruthenium red (10 microM) and ryanodine (10 microM), but not by the inositol 1,4,5-trisphosphate receptor blocker heparin (0.5 mg/ml). Ruthenium Red 171-184 ryanodine receptor 1, skeletal muscle Mus musculus 158-161 9142939-6 1997 In contrast, ruthenium red, a RyR antagonist, completely abolished ACh-induced [Ca2+]i oscillations. Ruthenium Red 13-26 ryanodine receptor 1, skeletal muscle Mus musculus 30-33 24863930-6 2014 Furthermore, a large conductance nonspecific cation channel, which was identified previously in the vesicle membrane and has biophysical properties similar to that of an RyR, is pharmacologically affected in a manner characteristic of an RyR: it is activated in the presence of the RyR agonist ryanodine (at low concentrations) and blocked by the RyR antagonist ruthenium red. Ruthenium Red 362-375 ryanodine receptor 1, skeletal muscle Mus musculus 238-241 24863930-6 2014 Furthermore, a large conductance nonspecific cation channel, which was identified previously in the vesicle membrane and has biophysical properties similar to that of an RyR, is pharmacologically affected in a manner characteristic of an RyR: it is activated in the presence of the RyR agonist ryanodine (at low concentrations) and blocked by the RyR antagonist ruthenium red. Ruthenium Red 362-375 ryanodine receptor 1, skeletal muscle Mus musculus 238-241 15036951-4 2004 FK506-induced [Ca(2+)](i) increase was completely blocked by the RyR antagonist ruthenium red and ryanodine, but not the IP(3)R antagonist heparin. Ruthenium Red 80-93 ryanodine receptor 1, skeletal muscle Mus musculus 65-68 10807666-5 2000 Sanguinarine induced Ca(2+) release from the actively loaded SR vesicles was blocked by ruthenium red and dithiothreitol (DTT), consistent with the ryanodine receptor (RyR) as the site of sanguinarine action. Ruthenium Red 88-101 ryanodine receptor 1, skeletal muscle Mus musculus 168-171