PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34765643-5	2021	Using a highly selective small-molecule BRD4 inhibitor (ZL0454) developed by us, we extend these findings to identify the gene regulatory network dependent on BRD4 bromodomain (BD) interactions.	CHEMBL4159382	56-62	bromodomain containing 4	Homo sapiens	40-44	
34765643-5	2021	Using a highly selective small-molecule BRD4 inhibitor (ZL0454) developed by us, we extend these findings to identify the gene regulatory network dependent on BRD4 bromodomain (BD) interactions.	CHEMBL4159382	56-62	bromodomain containing 4	Homo sapiens	159-163	
30321559-13	2019	A novel small-molecule BRD4 inhibitor (ZL0454) disrupts BRD4 binding to the NF-kappaB-RNA polymerase II complex and inhibits its histone acetyltransferase activity.	CHEMBL4159382	39-45	bromodomain containing 4	Homo sapiens	23-27	
30321559-13	2019	A novel small-molecule BRD4 inhibitor (ZL0454) disrupts BRD4 binding to the NF-kappaB-RNA polymerase II complex and inhibits its histone acetyltransferase activity.	CHEMBL4159382	39-45	bromodomain containing 4	Homo sapiens	56-60	
29649741-2	2018	Compounds ZL0420 (28) and ZL0454 (35) were identified as potent and selective BRD4 inhibitors with nanomolar binding affinities to bromodomains (BDs) of BRD4.	CHEMBL4159382	26-32	bromodomain containing 4	Homo sapiens	78-82	
30153047-4	2019	We therefore tested two novel highly selective BRD4 inhibitors, ZL0420 and ZL0454, for their effects on chronic airway remodeling produced by repetitive TLR3 agonist challenges, and compared their efficacy with that of two nonselective bromodomain and extraterminal (BET) protein inhibitors, JQ1 and RVX208.	CHEMBL4159382	75-81	bromodomain containing 4	Homo sapiens	47-51	
29649741-2	2018	Compounds ZL0420 (28) and ZL0454 (35) were identified as potent and selective BRD4 inhibitors with nanomolar binding affinities to bromodomains (BDs) of BRD4.	CHEMBL4159382	26-32	bromodomain containing 4	Homo sapiens	153-157