PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11347816-14	2001	The 5HT1A/5HT7 agonist 8-hydroxy DPAT inhibited both the nicotine and GABA-evoked release of dopamine.	8-Hydroxy-2-(di-n-propylamino)tetralin	23-37	5-hydroxytryptamine receptor 1A	Oryctolagus cuniculus	4-9	
2547897-4	1989	The 5-HT1A [5-hydroxytryptamine (serotonin) type 1A] receptor agonists 8-hydroxy-2-(di-n-propylamino)tetralin and buspirone mimic the serotonin response in reducing the forskolin-stimulated cyclic AMP levels, as do the indole derivatives 5-methoxytryptamine, 5-hydroxtryptophan, and tryptamine.	8-Hydroxy-2-(di-n-propylamino)tetralin	71-109	5-hydroxytryptamine receptor 1A	Oryctolagus cuniculus	4-10	
12909675-5	2003	The 5-HT1A agonist 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT; 0.1 mg kg-1 I.V.)	8-Hydroxy-2-(di-n-propylamino)tetralin	19-57	5-hydroxytryptamine receptor 1A	Oryctolagus cuniculus	4-10	
1969119-6	1990	These findings indicated that 8-OH-DPAT and SM-3997 inhibited the hippocampal RSA by acting on hippocampal 5-HT1A receptors.	8-Hydroxy-2-(di-n-propylamino)tetralin	30-39	5-hydroxytryptamine receptor 1A	Oryctolagus cuniculus	107-113	
9503254-3	1997	At high concentrations, the 5-HT1A agonist 8-OH-DPAT attenuated the carbachol-induced stimulation of inositol phosphates (InsPs) production, but this was not blocked by the presence of 5-HT1A antagonists.	8-Hydroxy-2-(di-n-propylamino)tetralin	43-52	5-hydroxytryptamine receptor 1A	Oryctolagus cuniculus	28-34	
8878215-4	1996	Topical application of the 5-HT1A agonist, 8-hydroxydipropylaminotetralin (8-OH-DPAT) reduces intraocular pressure (IOP).	8-Hydroxy-2-(di-n-propylamino)tetralin	75-84	5-hydroxytryptamine receptor 1A	Oryctolagus cuniculus	27-33	
7558717-9	1995	Inhibition studies with [3H] 5-HT plus 100 nM 8-OH-DPAT (which inhibits binding to 5-HT1A receptors only) representing total binding, indicated that no further displacement occurred when ligands preferentially selective for 5-HT1B, 5-HT1D alpha,1D beta, or 5-HT2C were tested.	8-Hydroxy-2-(di-n-propylamino)tetralin	46-55	5-hydroxytryptamine receptor 1A	Oryctolagus cuniculus	83-89	
1969119-4	1990	The effects of 8-OH-DPAT and SM-3997 on the hippocampal RSA were blocked by pindolol, which has 5-HT1A antagonistic activity.	8-Hydroxy-2-(di-n-propylamino)tetralin	15-24	5-hydroxytryptamine receptor 1A	Oryctolagus cuniculus	96-102	
10454495-5	1999	Likewise, WAY 100635 (10(-6) M) inhibited contraction to the 5-HT(1A) receptor agonists (+/-)-8-hydroxydipropylaminotetralin hydrobromide (8-OH-DPAT) and LY238729, without altering contraction to norepinephrine or sumatriptan.	8-Hydroxy-2-(di-n-propylamino)tetralin	139-148	5-hydroxytryptamine receptor 1A	Oryctolagus cuniculus	61-68	
9375958-22	1997	It appears that the enhancement of reflexes by 8-OH-DPAT arises from a combined action at 5-HT1A-receptors and other, ritanserin-sensitive, sites which could be 5-HT1D- or 5-HT7-receptors.	8-Hydroxy-2-(di-n-propylamino)tetralin	47-56	5-hydroxytryptamine receptor 1A	Oryctolagus cuniculus	90-96	
8111640-1	1993	Cigarette smoke passed through the nasal cavity of atenolol pre-treated anesthetized spontaneously breathing rabbits caused a bradycardia which was significantly modified by intracisternal application of the 5-HT1A receptor ligands 8-OH-DPAT (50 micrograms.kg-1) and buspirone (200 micrograms.kg-1).	8-Hydroxy-2-(di-n-propylamino)tetralin	232-241	5-hydroxytryptamine receptor 1A	Oryctolagus cuniculus	208-214	
8405187-3	1993	The inhibitory effects of 5-CT and the 5-HT1A selective agent 8-hydroxy-2-(di-n-propyl-amino) tetralin (8-OH-DPAT) on forskolin stimulated adenylate cyclase activity are greater in isolated ciliary processes than in the iris musculature.	8-Hydroxy-2-(di-n-propylamino)tetralin	62-102	5-hydroxytryptamine receptor 1A	Oryctolagus cuniculus	39-45	
8405187-3	1993	The inhibitory effects of 5-CT and the 5-HT1A selective agent 8-hydroxy-2-(di-n-propyl-amino) tetralin (8-OH-DPAT) on forskolin stimulated adenylate cyclase activity are greater in isolated ciliary processes than in the iris musculature.	8-Hydroxy-2-(di-n-propylamino)tetralin	104-113	5-hydroxytryptamine receptor 1A	Oryctolagus cuniculus	39-45	
8222726-3	1993	This effect is also induced by the 5-HT receptor agonists 8-OH-DPAT (8-hydroxy-2-[di-n-propyl-amino] tetralin, RU 24969 (5-methoxy-3-[1,2,3,6, tetrahydro-4-pyridinyl]-1-indole) and ipsapirone, suggesting the involvement of 5-HT1A receptors.	8-Hydroxy-2-(di-n-propylamino)tetralin	58-67	5-hydroxytryptamine receptor 1A	Oryctolagus cuniculus	223-229	
1682325-2	1991	In the isolated perfused mesenteric bed of the rat, bolus administration or infusion of the selective 5-HT1A receptor agonist 8-hydroxy-2-(di-n-propyl-amino) tetralin (8-OH-DPAT; bolus 0.3-90 nmoles, infusion 0.03-30 microM) caused dose-related decreases in phenylephrine-induced tone.	8-Hydroxy-2-(di-n-propylamino)tetralin	168-177	5-hydroxytryptamine receptor 1A	Oryctolagus cuniculus	102-108