PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
8857590-11	1996	The 8-OH-DPAT effect also is likely mediated by 5-HT1D receptors; stereoselectivity was found with its enantiomers at this receptor site and the effect was blocked by ketanserin (1 microM) but not by spiperone (1 microM).	8-Hydroxy-2-(di-n-propylamino)tetralin	4-13	5-hydroxytryptamine receptor 1D	Homo sapiens	48-54	
2252308-9	1990	5-HT1D receptors show high to intermediate affinities to compounds such as PAPP, DP-5-CT, 8-OH-DPAT, yohimbine and rauwolscine, whereas 5-HT1B receptors have very low affinities for these compounds.	8-Hydroxy-2-(di-n-propylamino)tetralin	90-99	5-hydroxytryptamine receptor 1D	Homo sapiens	0-6	
2521959-6	1989	Drug interactions with putative 5-HT1D binding sites in bovine caudate membranes correlated significantly with their affinities for human membrane recognition sites labeled by 3H-5-HT in the presence of 100 nM 8-OH-DPAT + 100 nM mesulergine.	8-Hydroxy-2-(di-n-propylamino)tetralin	210-219	5-hydroxytryptamine receptor 1D	Homo sapiens	32-38	
3399126-5	1988	5-HT1D sites were defined as the binding sites remaining when both 8-OH-DPAT and mesulergine were added to the incubation medium.	8-Hydroxy-2-(di-n-propylamino)tetralin	67-76	5-hydroxytryptamine receptor 1D	Homo sapiens	0-6	
9871775-4	1998	Surprisingly enough, the dimer of 8-OH-DPAT 6 binds to 5HT1A, 5HT1B and 5HT1D receptors with similar high affinity.	8-Hydroxy-2-(di-n-propylamino)tetralin	34-43	5-hydroxytryptamine receptor 1D	Homo sapiens	72-77	
8741179-2	1996	R(+)-8-OH-DPAT demonstrated potent intrinsic activity (EC50 value: 30 nM) at 5-HT1D alpha receptor sites, its maximal effect being comparable to that of sumatriptan.	8-Hydroxy-2-(di-n-propylamino)tetralin	0-14	5-hydroxytryptamine receptor 1D	Homo sapiens	77-89