PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10860641-4 2000 m CPP (2.5 mg kg(-1)), DOI (2.5 mg kg(-1)) and 8-OH-DPAT (1 mg kg(-1)) increased the serum PRL levels to a similar value, without affecting FSH and LH concentrations. 8-Hydroxy-2-(di-n-propylamino)tetralin 47-56 prolactin Rattus norvegicus 91-94 7753334-0 1995 Differential sites of action of 8OHDPAT, a 5HT1A agonist, on ACTH and PRL secretion in the rat. 8-Hydroxy-2-(di-n-propylamino)tetralin 32-39 prolactin Rattus norvegicus 70-73 10221360-0 1999 Effect of a long-term low tryptophan diet on the prolactin responses to the 5-HT1A and 5-HT2C agonists, 8-OH-DPAT and mCPP in the male rat. 8-Hydroxy-2-(di-n-propylamino)tetralin 104-113 prolactin Rattus norvegicus 49-58 8614270-2 1996 8-OH-DPAT dose-dependently (0.1-10 microgram/rat, icv) stimulated serum PRL levels, and depressed serotonergic neuron activity in 30 min. 8-Hydroxy-2-(di-n-propylamino)tetralin 0-9 prolactin Rattus norvegicus 72-75 8614270-0 1996 Central administration of 8-OH-DPAT and mCPP stimulates prolactin secretion in ovariectomized, estrogen-treated rats: lack of an effect on tuberoinfundibular dopaminergic neuron activity. 8-Hydroxy-2-(di-n-propylamino)tetralin 26-35 prolactin Rattus norvegicus 56-65 7753334-2 1995 In order to explore the possible neuroanatomical structures involved in this interaction, we examined ACTH and PRL responses to intracerebral infusions of the 5HT1A receptor agonist 8-hydroxy-2-(di-n-propylamino) tetralin (8OHDPAT). 8-Hydroxy-2-(di-n-propylamino)tetralin 182-221 prolactin Rattus norvegicus 111-114 7753334-6 1995 Infusion of 8OHDPAT (1 microgram/microliter/15 min) into the dorsal raphe nucleus induced a slow elevation of ACTH release but was ineffective on PRL secretion while infusion of 8OHDPAT into the PVN induced a moderate elevation of both ACTH and PRL. 8-Hydroxy-2-(di-n-propylamino)tetralin 12-19 prolactin Rattus norvegicus 245-248 7753334-6 1995 Infusion of 8OHDPAT (1 microgram/microliter/15 min) into the dorsal raphe nucleus induced a slow elevation of ACTH release but was ineffective on PRL secretion while infusion of 8OHDPAT into the PVN induced a moderate elevation of both ACTH and PRL. 8-Hydroxy-2-(di-n-propylamino)tetralin 178-185 prolactin Rattus norvegicus 245-248 7753334-7 1995 After bilateral destruction of the PVN, PRL response to 8OHDPAT (0.1 and 0.25 mg/kg) was markedly potentiated. 8-Hydroxy-2-(di-n-propylamino)tetralin 56-63 prolactin Rattus norvegicus 40-43 25220702-8 2014 In contrast, prolactin levels remained similar to those of controls both in hyperestrogenic animals treated with 8-OH-DPAT and pindolol and in hypoestrogenic rats administered the same treatments. 8-Hydroxy-2-(di-n-propylamino)tetralin 113-122 prolactin Rattus norvegicus 13-22 8113999-2 1994 5-HT-1A receptor agonists, such as 8-hydroxy-2-(di-n-propyl-amino)tetralin, increase the plasma prolactin concentration in rats, probably by an action in the brain that leads to an increase in prolactin release from the pituitary gland. 8-Hydroxy-2-(di-n-propylamino)tetralin 35-74 prolactin Rattus norvegicus 96-105 8113999-2 1994 5-HT-1A receptor agonists, such as 8-hydroxy-2-(di-n-propyl-amino)tetralin, increase the plasma prolactin concentration in rats, probably by an action in the brain that leads to an increase in prolactin release from the pituitary gland. 8-Hydroxy-2-(di-n-propylamino)tetralin 35-74 prolactin Rattus norvegicus 193-202 7510111-7 1993 In addition, the simultaneous increase in serum and pituitary prolactin content suggests that 8-OH-DPAT enhances prolactin synthesis. 8-Hydroxy-2-(di-n-propylamino)tetralin 94-103 prolactin Rattus norvegicus 62-71 7510111-7 1993 In addition, the simultaneous increase in serum and pituitary prolactin content suggests that 8-OH-DPAT enhances prolactin synthesis. 8-Hydroxy-2-(di-n-propylamino)tetralin 94-103 prolactin Rattus norvegicus 113-122 1982341-0 1990 Diminished corticotropin and enhanced prolactin responses to 8-hydroxy-2(di-n-propylamino)tetralin in methylenedioxymethamphetamine pretreated rats. 8-Hydroxy-2-(di-n-propylamino)tetralin 61-98 prolactin Rattus norvegicus 38-47 1982341-2 1990 In the present study, a blunted corticotropin and an enhanced prolactin response to the 5-HT1A agonist 8-hydroxy-2(di-n-propylamino)tetralin (8-OH DPAT) was found in rats treated two weeks previously with a single dose of MDMA (2.0 or 20.0 mg/kg, sc). 8-Hydroxy-2-(di-n-propylamino)tetralin 103-140 prolactin Rattus norvegicus 62-71 1982341-2 1990 In the present study, a blunted corticotropin and an enhanced prolactin response to the 5-HT1A agonist 8-hydroxy-2(di-n-propylamino)tetralin (8-OH DPAT) was found in rats treated two weeks previously with a single dose of MDMA (2.0 or 20.0 mg/kg, sc). 8-Hydroxy-2-(di-n-propylamino)tetralin 142-151 prolactin Rattus norvegicus 62-71 2940798-0 1986 A central serotonin receptor agonist, 8-hydroxy-2-(di-n-propylamino)tetralin, has different effects on prolactin secretion in male and female rats. 8-Hydroxy-2-(di-n-propylamino)tetralin 38-76 prolactin Rattus norvegicus 103-112 2940798-1 1986 Male and female rats were compared with respect to alterations in prolactin secretion induced by the serotonin receptor agonist 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT). 8-Hydroxy-2-(di-n-propylamino)tetralin 128-166 prolactin Rattus norvegicus 66-75 2940798-1 1986 Male and female rats were compared with respect to alterations in prolactin secretion induced by the serotonin receptor agonist 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT). 8-Hydroxy-2-(di-n-propylamino)tetralin 168-177 prolactin Rattus norvegicus 66-75 2940798-4 1986 In females, in contrast, 0.1 mg/kg of 8-OH-DPAT tended to decrease serum levels of prolactin, while 0.3, 1, and 3 mg/kg elevated them in a dose dependent manner to maximally 700% of control values. 8-Hydroxy-2-(di-n-propylamino)tetralin 38-47 prolactin Rattus norvegicus 83-92 2940798-6 1986 In males, but not in females, pretreatment with 8-OH-DPAT (1 mg/kg) reduced the 5-MeODMT-induced elevation of serum prolactin levels. 8-Hydroxy-2-(di-n-propylamino)tetralin 48-57 prolactin Rattus norvegicus 116-125 2940798-7 1986 The mechanism underlying the sexually differentiated effects of 8-OH-DPAT on prolactin secretion is discussed. 8-Hydroxy-2-(di-n-propylamino)tetralin 64-73 prolactin Rattus norvegicus 77-86 7510111-0 1993 Gonadotropin and prolactin secretion in prepubertal female rats treated with 8-hydroxy-2-(di-n-propylamino) tetralin. 8-Hydroxy-2-(di-n-propylamino)tetralin 77-116 prolactin Rattus norvegicus 17-26 1357574-2 1992 The serotonin1A receptor agonist, 8-hydroxy-2(di-n-propylamino) tetralin (8-OHDPAT) increased concentrations of prolactin in plasma rapidly and in a dose-related manner. 8-Hydroxy-2-(di-n-propylamino)tetralin 34-72 prolactin Rattus norvegicus 112-121 1357574-2 1992 The serotonin1A receptor agonist, 8-hydroxy-2(di-n-propylamino) tetralin (8-OHDPAT) increased concentrations of prolactin in plasma rapidly and in a dose-related manner. 8-Hydroxy-2-(di-n-propylamino)tetralin 74-82 prolactin Rattus norvegicus 112-121 1357574-3 1992 Concentrations of prolactin peaked within 9 min after intravenous injection of 8-OHDPAT and returned to baseline values within 30 min. 8-Hydroxy-2-(di-n-propylamino)tetralin 79-87 prolactin Rattus norvegicus 18-27 1350068-2 1992 The purposes of the present studies were to determine if nicotine, morphine and the serotonin1A (5-HT1A) agonist 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT) utilize a common synaptic pathway to release prolactin and, if so, to establish the serial order of the receptors involved. 8-Hydroxy-2-(di-n-propylamino)tetralin 113-151 prolactin Rattus norvegicus 209-218 1350068-5 1992 In the saline-treated animals, administration of nicotine, morphine, 8-OH-DPAT and haloperidol resulted in significant increases in plasma prolactin levels. 8-Hydroxy-2-(di-n-propylamino)tetralin 69-78 prolactin Rattus norvegicus 139-148 1350068-11 1992 These data indicate that nicotine, morphine and 8-OH-DPAT act to release prolactin via a common synaptic pathway expressing nicotinic cholinergic, opiate, and 5-HT1A receptors at synapses arranged serially in that functional order. 8-Hydroxy-2-(di-n-propylamino)tetralin 48-57 prolactin Rattus norvegicus 73-82