PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32396921-7 2020 In addition, mPFC infusion of 8-OH-DPAT increased the phosphorylation of signaling proteins downstream of BDNF, including mTOR, ERK, 4EBP1, and p70S6K. 8-Hydroxy-2-(di-n-propylamino)tetralin 30-39 mitogen-activated protein kinase 1 Homo sapiens 128-131 18607571-3 2008 Stimulation with the 5-HT(1A/7) receptor agonist, 8-OH-DPAT, reduced P-T(185)/Y(187)-ERK2. 8-Hydroxy-2-(di-n-propylamino)tetralin 50-59 mitogen-activated protein kinase 1 Homo sapiens 85-89 18607571-5 2008 Pretreatment with the cholesterol sequestering agent, methyl-beta-cyclodextrin, before adding 8-OH-DPAT, significantly counteracted the inhibitory influence of 8-OH-DPAT on P-T(185)/Y(187)-ERK2 and P-S(133)-CREB. 8-Hydroxy-2-(di-n-propylamino)tetralin 160-169 mitogen-activated protein kinase 1 Homo sapiens 189-193 12676358-7 2003 Finally, transient expression of kinase-negative PKCalpha eliminated the 8-OH-DPAT-evoked block on the H(2)O(2)-triggered caspase-3 stimulation, establishing PKCalpha as a link between ERK and caspase-3 (5-HT(1A)-R-->PLC-->ERK1/2-->PKCalpha-->caspase-3). 8-Hydroxy-2-(di-n-propylamino)tetralin 73-82 mitogen-activated protein kinase 1 Homo sapiens 185-188 8798386-3 1996 Activation of ERK2 by the 5-HT1A receptor-selective agonist 8-hydroxy-N,N-dipropyl-2-aminotetralin hydrobromide (8-OH-DPAT) was inhibited completely by pertussis toxin and substantially by prolonged treatment of cells with phorbol 12-myristate 13-acetate. 8-Hydroxy-2-(di-n-propylamino)tetralin 60-111 mitogen-activated protein kinase 1 Homo sapiens 14-18 8798386-3 1996 Activation of ERK2 by the 5-HT1A receptor-selective agonist 8-hydroxy-N,N-dipropyl-2-aminotetralin hydrobromide (8-OH-DPAT) was inhibited completely by pertussis toxin and substantially by prolonged treatment of cells with phorbol 12-myristate 13-acetate. 8-Hydroxy-2-(di-n-propylamino)tetralin 113-122 mitogen-activated protein kinase 1 Homo sapiens 14-18 26876117-6 2016 Interestingly, co-incubation of heterodimer-expressing HEK 293 cells with clozapine and the 5-HT1 A R agonist 8-OH DPAT potentiated post-synaptic effects, especially with respect to ERK activation. 8-Hydroxy-2-(di-n-propylamino)tetralin 110-119 mitogen-activated protein kinase 1 Homo sapiens 182-185