PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8386213-5 1993 5-HT, 8-OH-DPAT (both at 10 nmol/l) and DOI (at higher concentrations) blunted the stimulatory effect of CRH. 8-Hydroxy-2-(di-n-propylamino)tetralin 6-15 corticotropin releasing hormone Rattus norvegicus 105-108 8945958-8 1996 The CRH antagonist alpha-helical CRH-(9-41) attenuated the increases in metabolic rate induced by DOI and 8-OH-DPAT. 8-Hydroxy-2-(di-n-propylamino)tetralin 106-115 corticotropin releasing hormone Rattus norvegicus 4-7 8945958-8 1996 The CRH antagonist alpha-helical CRH-(9-41) attenuated the increases in metabolic rate induced by DOI and 8-OH-DPAT. 8-Hydroxy-2-(di-n-propylamino)tetralin 106-115 corticotropin releasing hormone Rattus norvegicus 33-36 8386213-6 1993 The suppressive effects of 8-OH-DPAT and DOI on CRH-stimulated ACTH release were antagonized by (-)propranolol, a beta-adrenergic receptor antagonist which binds the 5-HT1A receptor with elevated affinity, and ketanserin, a 5-HT2 receptor antagonist respectively. 8-Hydroxy-2-(di-n-propylamino)tetralin 27-36 corticotropin releasing hormone Rattus norvegicus 48-51 1369587-6 1992 This same dose of 8-OH-DPAT also induced a decrease of hypothalamic CRH concentration, which was completely antagonized as well by pretreatment injection of (+/-)-pindolol into the PVN. 8-Hydroxy-2-(di-n-propylamino)tetralin 18-27 corticotropin releasing hormone Rattus norvegicus 68-71 2150776-5 1990 Pituitary stalk transection (PST), as well as pretreatment with rabbit serum hyperimmune against rat corticotropin-releasing hormone (CRH, TS-6) completely abolished beta-End-LI response to 8-OH-DPAT and attenuated the responses by about 60% to DOI. 8-Hydroxy-2-(di-n-propylamino)tetralin 190-199 corticotropin releasing hormone Rattus norvegicus 101-132 2150776-5 1990 Pituitary stalk transection (PST), as well as pretreatment with rabbit serum hyperimmune against rat corticotropin-releasing hormone (CRH, TS-6) completely abolished beta-End-LI response to 8-OH-DPAT and attenuated the responses by about 60% to DOI. 8-Hydroxy-2-(di-n-propylamino)tetralin 190-199 corticotropin releasing hormone Rattus norvegicus 134-137