PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30320262-4 2018 Considering that triterpenoids from natural sources have been identified as inhibitors of nuclear factor kappa-light-chain-enhancer of activated B cell (NF-kappaB) signaling, docking studies were conducted to evaluate whether NF-kappaB may be a potential target. triterpenoids 17-30 nuclear factor kappa B subunit 1 Homo sapiens 153-162 30320262-4 2018 Considering that triterpenoids from natural sources have been identified as inhibitors of nuclear factor kappa-light-chain-enhancer of activated B cell (NF-kappaB) signaling, docking studies were conducted to evaluate whether NF-kappaB may be a potential target. triterpenoids 17-30 nuclear factor kappa B subunit 1 Homo sapiens 226-235 25027934-1 2014 The new series of pentacyclic triterpenoids reduced lantadene A (3), B (4), and 22beta-hydroxy-3-oxo-olean-12-en-28-oic acid (5) analogs were synthesized and tested in vitro for their NF-kappaB and IKKbeta inhibitory potencies and cytotoxicity against A549 lung cancer cells. triterpenoids 30-43 nuclear factor kappa B subunit 1 Homo sapiens 184-193 30057155-0 2018 Cytotoxic and NF-kappaB and mitochondrial transmembrane potential inhibitory pentacyclic triterpenoids from Syzygium corticosum and their semi-synthetic derivatives. triterpenoids 89-102 nuclear factor kappa B subunit 1 Homo sapiens 14-23 23717159-0 2013 Oleanane-triterpenoids from Panax stipuleanatus inhibit NF-kappaB. triterpenoids 9-22 nuclear factor kappa B subunit 1 Homo sapiens 56-65 19213570-11 2009 Moreover, from immunofluorescence experiments we observed that treatment with these triterpenoids prevents nuclear factor NF-kappaB translocation into the nucleus and thereby the activation of downstream pathways. triterpenoids 84-97 nuclear factor kappa B subunit 1 Homo sapiens 122-131 24457265-1 2014 The C-3, C-17 and C-22 congeners of pentacyclic triterpenoids reduced lantadene A (3), B (4) and 22beta-hydroxyoleanolic acid (5) were synthesized and were tested in vitro for their NF-kappaB and IKKbeta inhibitory potencies and cytotoxicity against A549 lung cancer cells. triterpenoids 48-61 nuclear factor kappa B subunit 1 Homo sapiens 182-191 22659375-3 2012 Docking results suggested that both the triterpenoids (1 and 2) showed immune modulatory and anti-inflammatory activity due to high binding affinity to human receptors viz., NF-kappaB p52 (-50.549 kcal/mol), tumor necrosis factor (TNF-alpha) (-47.632 kcal/mol), nuclear factor NF-Kappa-B P50 (-16.798 kcal/mol) and cyclooxygenase-2 (-55.244 kcal/mol). triterpenoids 40-53 nuclear factor kappa B subunit 1 Homo sapiens 277-291 20392997-0 2010 Synthetic triterpenoids inhibit growth, induce apoptosis and suppress pro-survival Akt, mTOR and NF-{kappa}B signaling proteins in colorectal cancer cells. triterpenoids 10-23 nuclear factor kappa B subunit 1 Homo sapiens 97-108 18608528-0 2008 Immunomodulatory activity of synthetic triterpenoids: inhibition of lymphocyte proliferation, cell-mediated cytotoxicity, and cytokine gene expression through suppression of NF-kappaB. triterpenoids 39-52 nuclear factor kappa B subunit 1 Homo sapiens 174-183