PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21880714-0 2011 Ligand-receptor interaction between triterpenoids and the 11beta-hydroxysteroid dehydrogenase type 2 (11betaHSD2) enzyme predicts their toxic effects against tumorigenic r/m HM-SFME-1 cells. triterpenoids 36-49 hydroxysteroid 11-beta dehydrogenase 2 Mus musculus 102-112 21880714-2 2011 Ligand fitting of five different triterpenoids to 11beta-hydroxysteroid dehydrogenase type 2 (11betaHSD2) was analyzed with a molecular modeling method, and glycyrrhetinic acid (GA) was the best-fitted triterpenoid to the ligand binding site in 11betaHSD2. triterpenoids 33-46 hydroxysteroid 11-beta dehydrogenase 2 Mus musculus 94-104 21880714-8 2011 To the best of our knowledge, this is the first report on in silico prediction of the toxic effects of triterpenoids on tumor cells by 11betaHSD2 inhibition. triterpenoids 103-116 hydroxysteroid 11-beta dehydrogenase 2 Mus musculus 135-145