PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26084365-9	2015	CONCLUSION: Our results in apoE(-/-) mice suggest that even under strong genetic predisposition to hypercholesterolemia, pups born to mothers supplemented with phytosterols during gestation and lactation exhibit favorable liver and serum lipid responses compared with pups from unsupplemented mothers.	Phytosterols	160-172	apolipoprotein E	Mus musculus	27-31	
30739226-0	2019	Phytosterol containing diet increases plasma and whole body concentration of phytosterols in apoE-KO but not in LDLR-KO mice.	Phytosterols	0-11	apolipoprotein E	Mus musculus	93-97	
30739226-4	2019	ApoE-KO mice absorbed less phytosterols than LDLR-KO and the latter absorbed less phytosterols than control mice, because the intestinal campesterol content was low in both KO mice, and sitosterol was low in the intestine in apoE-KO mice as compared to LDLR-KO mice.	Phytosterols	27-39	apolipoprotein E	Mus musculus	0-4	
26084365-0	2015	Maternal Phytosterol Supplementation during Pregnancy and Lactation Modulates Lipid and Lipoprotein Response in Offspring of apoE-Deficient Mice.	Phytosterols	9-20	apolipoprotein E	Mus musculus	125-129	
26084365-3	2015	OBJECTIVE: This study used the hypercholesterolemic apolipoprotein E-deficient (apoE(-/-)) mouse model to test the hypothesis that mothers supplemented with phytosterols during gestation and lactation would produce offspring with a more favorable lipid profile than offspring from unsupplemented mothers, despite having a genetic predisposition toward hypercholesterolemia.	Phytosterols	157-169	apolipoprotein E	Mus musculus	80-84	
34365732-10	2021	CONCLUSIONS: This study revealed that phytosterols, COPs and POPs differently changed the composition and metabolism of glycerophospholipids, sphingolipids and glycerolipids in liver of ApoE-/- mice.	Phytosterols	38-50	apolipoprotein E	Mus musculus	186-190	
29675736-3	2018	Plasma cholesterol and phytosterols (campesterol and sitosterol) were higher in apoE-KO compared to control mice.	Phytosterols	23-35	apolipoprotein E	Mus musculus	80-84	
29084592-0	2017	Transcriptional control of enterohepatic lipid regulatory targets in response to early cholesterol and phytosterol exposure in apoE-/- mice.	Phytosterols	103-114	apolipoprotein E	Mus musculus	127-131	
29084592-2	2017	We characterized how maternal phytosterol (PS) supplementation affected serum lipids and the expression of lipid-regulatory genes in the intestine and liver of newly-weaned apo-E deficient offspring from dams fed a chow diet supplemented with cholesterol (0.15%, CH) or cholesterol and PS (2%) (CH/PS) throughout pregnancy and lactation.	Phytosterols	30-41	apolipoprotein E	Mus musculus	173-178	
29084592-2	2017	We characterized how maternal phytosterol (PS) supplementation affected serum lipids and the expression of lipid-regulatory genes in the intestine and liver of newly-weaned apo-E deficient offspring from dams fed a chow diet supplemented with cholesterol (0.15%, CH) or cholesterol and PS (2%) (CH/PS) throughout pregnancy and lactation.	Phytosterols	43-45	apolipoprotein E	Mus musculus	173-178	
17382351-5	2007	However, cultured spleen lymphocytes of apoE(-/-) mice fed with phytosterols and treated with turpentine showed increased IL-2 and IFN-gamma secretion (T-helper type1, Th1 lymphocyte cytokines) compared with turpentine-treated, control-fed animals.	Phytosterols	64-76	apolipoprotein E	Mus musculus	40-44	
18155511-8	2008	In summary, our data suggest that long-term dietary phytosterols can alter the expression of a number of hepatic genes that regulate sterol metabolism in apo E-KO mice.	Phytosterols	52-64	apolipoprotein E	Mus musculus	154-159	
18155511-1	2008	Dietary phytosterols significantly reduce plasma cholesterol concentrations and atherosclerosis in apolipoprotein E-knockout (apo E-KO) mice.	Phytosterols	8-20	apolipoprotein E	Mus musculus	126-131	
17382351-9	2007	The Th1/Th2 ratio was significantly increased both in phytosterol-fed apoE(-/-) and C57BL/6J mice.	Phytosterols	54-65	apolipoprotein E	Mus musculus	70-74	
15939057-7	2005	ABCA1, ABCG5, ABCG8 and NPC1L1 mRNA levels were slightly reduced in the intestine of phytosterol-treated apoE(-/-) and LDLR(-/-) mice, but increased in C57BL/6J-treated mice.	Phytosterols	85-96	apolipoprotein E	Mus musculus	105-109	
16436964-0	2006	Dietary phytosterols reduce cyclosporine-induced hypercholesterolemia in apolipoprotein E-knockout mice.	Phytosterols	8-20	apolipoprotein E	Mus musculus	73-89	
17218830-6	2007	Recent animal studies suggest that phytosterols reduce atherosclerosis in the Apo-E deficient mouse model.	Phytosterols	35-47	apolipoprotein E	Mus musculus	78-83	
9012646-0	1997	"Tall oil"-derived phytosterols reduce atherosclerosis in ApoE-deficient mice.	Phytosterols	19-31	apolipoprotein E	Mus musculus	58-62	
10092072-10	1999	We conclude that addition of the phytosterol mixture (2% w/w) to a Western-type diet in apolipoprotein E-deficient mice significantly decreases plasma and hepatic cholesterol concentrations, increases hepatic 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity, and prevents cutaneous xanthomatosis and vacuolation in the parenchymal cells of kidneys and livers.	Phytosterols	33-44	apolipoprotein E	Mus musculus	88-104	
11398149-7	2001	Treatment of apo E-KO mice with either probucol or phytosterols significantly reduced plasma cholesterol levels.	Phytosterols	51-63	apolipoprotein E	Mus musculus	13-18