PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27402728-0	2016	CYP3A Specifically Catalyzes 1beta-Hydroxylation of Deoxycholic Acid: Characterization and Enzymatic Synthesis of a Potential Novel Urinary Biomarker for CYP3A Activity.	1,2-Di(anthracen-9-yl)ethyne	29-34	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	0-5	
18725509-10	2008	In conclusion, CYP3A4 was the major P450 isoform involved in MPA hydroxylation, with 6beta, 2beta, and 1beta being the possible hydroxylation sites.	1,2-Di(anthracen-9-yl)ethyne	103-108	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	15-21	
34073662-0	2021	Evaluation of 1beta-Hydroxylation of Deoxycholic Acid as a Non-Invasive Urinary Biomarker of CYP3A Activity in the Assessment of Inhibition-Based Drug-Drug Interaction in Healthy Volunteers.	1,2-Di(anthracen-9-yl)ethyne	14-19	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	93-98	
27402728-0	2016	CYP3A Specifically Catalyzes 1beta-Hydroxylation of Deoxycholic Acid: Characterization and Enzymatic Synthesis of a Potential Novel Urinary Biomarker for CYP3A Activity.	1,2-Di(anthracen-9-yl)ethyne	29-34	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	154-159	
27402728-7	2016	This indicated that 1beta-hydroxylation of DCA may be a useful marker reaction for CYP3A activity in vitro.	1,2-Di(anthracen-9-yl)ethyne	20-25	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	83-88	
27402728-9	2016	The potential utility of 1beta-hydroxylation of DCA as a urinary CYP3A biomarker was illustrated by comparing the ratio of 1beta-OH-DCA:DCA in a pooled spot urine sample from six healthy control subjects to a sample from one patient treated with carbamazepine, a potent CYP3A inducer; 1beta-OH-DCA:DCA was considerably higher in the patient versus controls (ratio 2.8 vs. 0.4).	1,2-Di(anthracen-9-yl)ethyne	25-30	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	65-70	
27402728-9	2016	The potential utility of 1beta-hydroxylation of DCA as a urinary CYP3A biomarker was illustrated by comparing the ratio of 1beta-OH-DCA:DCA in a pooled spot urine sample from six healthy control subjects to a sample from one patient treated with carbamazepine, a potent CYP3A inducer; 1beta-OH-DCA:DCA was considerably higher in the patient versus controls (ratio 2.8 vs. 0.4).	1,2-Di(anthracen-9-yl)ethyne	25-30	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	270-275