PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35128501-8	2022	Transcripts of viperin and CMPK2, enzymes responsible for ddhCTP synthesis, were amongst the five genes most highly correlated to ddhC abundance.	ddhCTP	58-64	radical S-adenosyl methionine domain containing 2	Homo sapiens	15-22	
34126010-1	2021	3"-Deoxy-3",4"-didehydro-cytidine triphosphate (ddhCTP) is a novel antiviral molecule produced by the enzyme viperin as part of the innate immune response.	ddhCTP	48-54	radical S-adenosyl methionine domain containing 2	Homo sapiens	109-116	
32232843-0	2020	ddhCTP produced by the radical-SAM activity of RSAD2 (viperin) inhibits the NAD+ -dependent activity of enzymes to modulate metabolism.	ddhCTP	0-6	radical S-adenosyl methionine domain containing 2	Homo sapiens	47-52	
32603630-4	2020	Most recently, however, viperin was demonstrated to catalyze the conversion of cytidine triphosphate (CTP) to 3"-deoxy-3",4"-didehydro-CTP (ddhCTP), a previously unknown ribonucleotide.	ddhCTP	140-146	radical S-adenosyl methionine domain containing 2	Homo sapiens	24-31	
32232843-0	2020	ddhCTP produced by the radical-SAM activity of RSAD2 (viperin) inhibits the NAD+ -dependent activity of enzymes to modulate metabolism.	ddhCTP	0-6	radical S-adenosyl methionine domain containing 2	Homo sapiens	54-61	
32232843-2	2020	Recently, it was found that RSAD2 catalyses transformation of cytidine triphosphate (CTP) to its analogue 3 -deoxy-3 ,4 -didehydro-CTP (ddhCTP).	ddhCTP	136-142	radical S-adenosyl methionine domain containing 2	Homo sapiens	28-33	
32232843-6	2020	We propose that ddhCTP regulates cellular metabolism in response to inflammatory stimuli such as viral infection, pointing to a broader function of RSAD2 than previously thought.	ddhCTP	16-22	radical S-adenosyl methionine domain containing 2	Homo sapiens	148-153	
30092190-3	2018	(2018) discovered that the ISG viperin inhibits virus replication by generating the ribonucleotide ddhCTP, which interferes with RNA synthesis, thus offering insights into drug design.	ddhCTP	99-105	radical S-adenosyl methionine domain containing 2	Homo sapiens	31-38	
29925952-4	2018	Here we demonstrate that viperin catalyses the conversion of cytidine triphosphate (CTP) to 3"-deoxy-3",4"-didehydro-CTP (ddhCTP), a previously undescribed biologically relevant molecule, via a SAM-dependent radical mechanism.	ddhCTP	122-128	radical S-adenosyl methionine domain containing 2	Homo sapiens	25-32	
29925952-5	2018	We show that mammalian cells expressing viperin and macrophages stimulated with IFNalpha produce substantial quantities of ddhCTP.	ddhCTP	123-129	radical S-adenosyl methionine domain containing 2	Homo sapiens	40-47