PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12575354-3 2002 The levels of IL-1 and sIL-2R from PBMC affected by 99Tc-MDP were determined with enzyme linked immunosorbert assays (ELISA). 99mTc-Methylene diphosphonate 52-60 interleukin 1 alpha Homo sapiens 14-18 12575354-4 2002 RESULTS: The IL-1 production by PBMC of RA, either in the medium alone (spontaneously) or in the presence of lipopolysacchride (LPS) stimulation, was suppressed by 99Tc-MDP; and the sIL-2R by PBMC of RA, either in the medium alone (spontaneously) or in the presence of phytohemagglutinin (PHA) induction, was inhibited by 99Tc-MDP. 99mTc-Methylene diphosphonate 164-172 interleukin 1 alpha Homo sapiens 13-17 12575354-4 2002 RESULTS: The IL-1 production by PBMC of RA, either in the medium alone (spontaneously) or in the presence of lipopolysacchride (LPS) stimulation, was suppressed by 99Tc-MDP; and the sIL-2R by PBMC of RA, either in the medium alone (spontaneously) or in the presence of phytohemagglutinin (PHA) induction, was inhibited by 99Tc-MDP. 99mTc-Methylene diphosphonate 322-330 interleukin 1 alpha Homo sapiens 13-17 12575354-5 2002 CONCLUSION: 99Tc-MDP acts on PBMC and a possible immune activity by 99Tc-MDP is related to the suppression of IL-1 and sIL-2R in RA patients. 99mTc-Methylene diphosphonate 12-20 interleukin 1 alpha Homo sapiens 110-114 12575354-5 2002 CONCLUSION: 99Tc-MDP acts on PBMC and a possible immune activity by 99Tc-MDP is related to the suppression of IL-1 and sIL-2R in RA patients. 99mTc-Methylene diphosphonate 68-76 interleukin 1 alpha Homo sapiens 110-114