PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28342081-5	2017	Further analysis revealed that PAH patterns in soil samples also showed some difference between secondary copper and aluminum smelter, which may be attributed to the difference in their fuel and smelting process.	Copper	106-112	phenylalanine hydroxylase	Homo sapiens	31-34	
33833848-0	2021	Optimizing CO Coverage on Rough Copper Electrodes: Effect of the Partial Pressure of CO and Electrolyte Anions (pH) on Selectivity toward Ethylene.	Copper	32-38	phenylalanine hydroxylase	Homo sapiens	112-114	
31896200-5	2020	Temperature and pH offer a synergistic effect on the adsorption of Cu (II), with maximum adsorption observed at pH 6.5 at 55  C. Kinetic, thermodynamic, and isotherm studies indicate that the adsorption of copper ions follows chemisorption and is thermodynamically favored at increasing temperature.	Copper	206-212	phenylalanine hydroxylase	Homo sapiens	16-18	
4854919-10	1974	Iron-chelating and copper-chelating agents inhibited human phenylalanine hydroxylase.	Copper	19-25	phenylalanine hydroxylase	Homo sapiens	59-84	
25228517-7	2014	In turn, mutations of the ATP7A and PAH genes, regulating intracellular copper concentration and activity of phenylalanine hydroxylase, lead to Menkes syndrome and phenylketonuria.	Copper	72-78	phenylalanine hydroxylase	Homo sapiens	109-134	
12588145-1	2003	The complex [(PAH)(4)Cu(II)(4)Cu(I)(2)Br(10)] (1) (PAH = picolinamide hydrazone) containing a Cu(II)(4)Cu(I)(2) hexanuclear cluster, with two well-separated Cu(II)(2) dinuclear centers, results from a redox reaction involving a hydrolytically unstable ligand, salicilyl picolinamide hydrazone, and CuBr(2) in aqueous acetonitrile.	Copper	21-23	phenylalanine hydroxylase	Homo sapiens	14-17	
12588145-1	2003	The complex [(PAH)(4)Cu(II)(4)Cu(I)(2)Br(10)] (1) (PAH = picolinamide hydrazone) containing a Cu(II)(4)Cu(I)(2) hexanuclear cluster, with two well-separated Cu(II)(2) dinuclear centers, results from a redox reaction involving a hydrolytically unstable ligand, salicilyl picolinamide hydrazone, and CuBr(2) in aqueous acetonitrile.	Copper	21-24	phenylalanine hydroxylase	Homo sapiens	14-17	
15962938-0	2005	Formation of 8-oxo-7,8-dihydro-2"-deoxyguanosine (8-oxo-dGuo) by PAH o-quinones: involvement of reactive oxygen species and copper(II)/copper(I) redox cycling.	Copper	124-130	phenylalanine hydroxylase	Homo sapiens	65-68	
15962938-0	2005	Formation of 8-oxo-7,8-dihydro-2"-deoxyguanosine (8-oxo-dGuo) by PAH o-quinones: involvement of reactive oxygen species and copper(II)/copper(I) redox cycling.	Copper	135-141	phenylalanine hydroxylase	Homo sapiens	65-68	
15962938-16	2005	These data showed that the production of 8-oxo-dGuo was dependent on Cu(II)/Cu(I) catalyzed redox cycling of PAH o-quinones to produce ROS and that the immediate oxidant was not hydroxyl radical or Cu(I)OOH and that it is more likely (1)O(2), which can produce a 4,8-endoperoxide-dGuo intermediate.	Copper	69-71	phenylalanine hydroxylase	Homo sapiens	109-112	
34546526-3	2022	The kinetic release experiment of the metal ion concentrations (nickel, chromium, titanium, iron, and copper) in the saliva uptakes follows a pseudo-second-order kinetic model; the release rate of metal ions was in series Fe2+ > Ti2+ > Ni2+ > Cu2+ > Cr3+, and the highest saliva pH and flow rate were detected after 1 month for fixed orthodontics appliance was (7.16 +- 0.55) and (0.88 +- 0.55) respectively.	Copper	102-108	phenylalanine hydroxylase	Homo sapiens	279-281	
34409178-4	2021	A laboratory study to replicate the phenomenon at bench-scale showed that either the algaecide itself or its copper-free acidic carrier can be used to depress pH and drive a reaction converting geosmin to an odorless dehydration product, argosmin.	Copper	109-115	phenylalanine hydroxylase	Homo sapiens	159-161	
35585102-0	2022	Quantifying local pH changes in carbonate electrolyte during copper-catalysed (Formula: see text) electroreduction using in operando (Formula: see text) NMR.	Copper	61-67	phenylalanine hydroxylase	Homo sapiens	18-20