PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33492639-11 2021 ZINC10157406 (2 x IC50) downregulated TCTP expression by 86.70 +- 0.44% and upregulated p53 expression by 177.60 +- 12.46%. 6-(4-fluorophenyl)-2-[(8-methoxy-4-methyl-2-quinazolinyl)amino]-4(3H)-pyrimidinone 0-12 tumor protein p53 Homo sapiens 88-91 33492639-12 2021 We validated ZINC10157406 binding to the p53 interaction site of TCTP and replacing p53 by co-immunoprecipitation. 6-(4-fluorophenyl)-2-[(8-methoxy-4-methyl-2-quinazolinyl)amino]-4(3H)-pyrimidinone 13-25 tumor protein p53 Homo sapiens 41-44