PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10962570-5 2000 Although the caspase 8 specific inhibitor z-IETD.fmk did not affect translocation of BAX to the mitochondrial membrane and cytochrome C release it almost completely blocked cleavage of the prototype caspase substrate PARP and DNA fragmentation while enforcing mitochondrial depolarization and production of reactive oxygene species (ROS). FMK 49-52 collagen type XI alpha 2 chain Homo sapiens 217-221 24727941-9 2014 Furthermore, the combined treatment markedly increased the cleaved PARP and cleaved caspase 3 in H460 cells, which were partly reversed by pretreatment with the caspase inhibitor zVAD.fmk. FMK 184-187 collagen type XI alpha 2 chain Homo sapiens 67-71 9129045-10 1997 Incubation of B-CLL cells with the CED-3/ICE-like protease inhibitor Z-VAD.fmk inhibited spontaneous and dexamethasone-induced PARP cleavage and DNA fragmentation in a dose-dependent manner. FMK 75-78 collagen type XI alpha 2 chain Homo sapiens 127-131