PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22865833-6	2012	The 7SK is known to influence the expression of a wide array of genes through its inhibitory effect on the positive transcription elongation factor b (P-TEFb) as well as its competing role in HMGA1-mediated transcriptional regulation.	(2s)-Tert-Butoxy[3-(3,4-Dihydro-2h-1-Benzopyran-6-Yl)-1-Methyl-1h-Indol-2-Yl]acetic Acid	4-7	high mobility group AT-hook 1	Homo sapiens	192-197	
23392246-3	2013	Here, we show that the 7SK RNA-associating chromatin regulator HMGA1 can specifically bind to the HIV-1 TAR element and that 7SK RNA can thereby compete with TAR.	(2s)-Tert-Butoxy[3-(3,4-Dihydro-2h-1-Benzopyran-6-Yl)-1-Methyl-1h-Indol-2-Yl]acetic Acid	23-26	high mobility group AT-hook 1	Homo sapiens	63-68	
23392246-6	2013	The overexpression of the HMGA1-binding substructure of 7SK RNA results in a TAR-dependent gain of HIV-1 promoter activity similar to the effect of the shRNA-mediated knockdown of HMGA1.	(2s)-Tert-Butoxy[3-(3,4-Dihydro-2h-1-Benzopyran-6-Yl)-1-Methyl-1h-Indol-2-Yl]acetic Acid	56-59	high mobility group AT-hook 1	Homo sapiens	26-31	
21282977-7	2011	The efficiency of interfering with HMGA1 transcription activity by the chimeric 7SK L2-EBER2 fusions by large exceeds the efficiency of 7SK wild-type RNA due to the stronger EBER2 promoter activity.	(2s)-Tert-Butoxy[3-(3,4-Dihydro-2h-1-Benzopyran-6-Yl)-1-Methyl-1h-Indol-2-Yl]acetic Acid	80-83	high mobility group AT-hook 1	Homo sapiens	35-40	
21282977-7	2011	The efficiency of interfering with HMGA1 transcription activity by the chimeric 7SK L2-EBER2 fusions by large exceeds the efficiency of 7SK wild-type RNA due to the stronger EBER2 promoter activity.	(2s)-Tert-Butoxy[3-(3,4-Dihydro-2h-1-Benzopyran-6-Yl)-1-Methyl-1h-Indol-2-Yl]acetic Acid	136-139	high mobility group AT-hook 1	Homo sapiens	35-40	
21282977-9	2011	The comparison of the effects of wild-type 7SK RNA on cellular transcriptome dynamics with those induced by the two 7SK L2 mutants as well as the changes in gene expression following inhibition of HMGA1 allow the identification and characterization of HMGA1-dependent and independent effects of 7SK snRNA.	(2s)-Tert-Butoxy[3-(3,4-Dihydro-2h-1-Benzopyran-6-Yl)-1-Methyl-1h-Indol-2-Yl]acetic Acid	43-46	high mobility group AT-hook 1	Homo sapiens	252-257	
21282977-9	2011	The comparison of the effects of wild-type 7SK RNA on cellular transcriptome dynamics with those induced by the two 7SK L2 mutants as well as the changes in gene expression following inhibition of HMGA1 allow the identification and characterization of HMGA1-dependent and independent effects of 7SK snRNA.	(2s)-Tert-Butoxy[3-(3,4-Dihydro-2h-1-Benzopyran-6-Yl)-1-Methyl-1h-Indol-2-Yl]acetic Acid	116-119	high mobility group AT-hook 1	Homo sapiens	252-257	
21282977-9	2011	The comparison of the effects of wild-type 7SK RNA on cellular transcriptome dynamics with those induced by the two 7SK L2 mutants as well as the changes in gene expression following inhibition of HMGA1 allow the identification and characterization of HMGA1-dependent and independent effects of 7SK snRNA.	(2s)-Tert-Butoxy[3-(3,4-Dihydro-2h-1-Benzopyran-6-Yl)-1-Methyl-1h-Indol-2-Yl]acetic Acid	116-119	high mobility group AT-hook 1	Homo sapiens	252-257	
21087998-4	2011	An important regulatory role of 7SK RNA in HMGA1-dependent cell differentiation and proliferation regulation is uncovered with the identification of over 1500 7SK-responsive HMGA1 target genes.	(2s)-Tert-Butoxy[3-(3,4-Dihydro-2h-1-Benzopyran-6-Yl)-1-Methyl-1h-Indol-2-Yl]acetic Acid	32-35	high mobility group AT-hook 1	Homo sapiens	43-48	
21087998-4	2011	An important regulatory role of 7SK RNA in HMGA1-dependent cell differentiation and proliferation regulation is uncovered with the identification of over 1500 7SK-responsive HMGA1 target genes.	(2s)-Tert-Butoxy[3-(3,4-Dihydro-2h-1-Benzopyran-6-Yl)-1-Methyl-1h-Indol-2-Yl]acetic Acid	32-35	high mobility group AT-hook 1	Homo sapiens	174-179	
21087998-4	2011	An important regulatory role of 7SK RNA in HMGA1-dependent cell differentiation and proliferation regulation is uncovered with the identification of over 1500 7SK-responsive HMGA1 target genes.	(2s)-Tert-Butoxy[3-(3,4-Dihydro-2h-1-Benzopyran-6-Yl)-1-Methyl-1h-Indol-2-Yl]acetic Acid	159-162	high mobility group AT-hook 1	Homo sapiens	43-48	
21087998-4	2011	An important regulatory role of 7SK RNA in HMGA1-dependent cell differentiation and proliferation regulation is uncovered with the identification of over 1500 7SK-responsive HMGA1 target genes.	(2s)-Tert-Butoxy[3-(3,4-Dihydro-2h-1-Benzopyran-6-Yl)-1-Methyl-1h-Indol-2-Yl]acetic Acid	159-162	high mobility group AT-hook 1	Homo sapiens	174-179	
21087998-5	2011	Elevated HMGA1 expression is observed in nearly every type of cancer making the use of a 7SK substructure in the inhibition of HMGA1 activity, as pioneered here, potentially useful in therapy.	(2s)-Tert-Butoxy[3-(3,4-Dihydro-2h-1-Benzopyran-6-Yl)-1-Methyl-1h-Indol-2-Yl]acetic Acid	89-92	high mobility group AT-hook 1	Homo sapiens	9-14	
21087998-5	2011	Elevated HMGA1 expression is observed in nearly every type of cancer making the use of a 7SK substructure in the inhibition of HMGA1 activity, as pioneered here, potentially useful in therapy.	(2s)-Tert-Butoxy[3-(3,4-Dihydro-2h-1-Benzopyran-6-Yl)-1-Methyl-1h-Indol-2-Yl]acetic Acid	89-92	high mobility group AT-hook 1	Homo sapiens	127-132	
21087998-6	2011	The 7SK-HMGA1 interaction not only adds an essential facet to the comprehension of transcriptional plasticity at the coupling of initiation and elongation, but also might provide a molecular link between HIV reprogramming of cellular gene expression-associated oncogenesis.	(2s)-Tert-Butoxy[3-(3,4-Dihydro-2h-1-Benzopyran-6-Yl)-1-Methyl-1h-Indol-2-Yl]acetic Acid	4-7	high mobility group AT-hook 1	Homo sapiens	8-13