PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 14701745-6 2004 Akt also antagonized tBID-mediated BAX activation and mitochondrial BAK oligomerization, two downstream events thought to be critical for tBID-induced apoptosis. tBID 21-25 AKT serine/threonine kinase 1 Homo sapiens 0-3 14701745-6 2004 Akt also antagonized tBID-mediated BAX activation and mitochondrial BAK oligomerization, two downstream events thought to be critical for tBID-induced apoptosis. tBID 138-142 AKT serine/threonine kinase 1 Homo sapiens 0-3 14701745-8 2004 Interestingly, tBID independently elicited dissociation of hexokinases from mitochondria, an effect that was antagonized by activated Akt. tBID 15-19 AKT serine/threonine kinase 1 Homo sapiens 134-137 14701745-10 2004 These results suggest that Akt inhibits BID-mediated apoptosis downstream of BID cleavage via promotion of mitochondrial hexokinase association and antagonism of tBID-mediated BAX and BAK activation at the mitochondria. tBID 162-166 AKT serine/threonine kinase 1 Homo sapiens 27-30