PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17030378-5 2007 SC-1 also activated intrinsic pathway via increase of pro-apoptotic (tBid, Bak and Bax) and decrease of anti-apoptotic (Bcl-2 and Bcl-x(L)) proteins on mitochondria, disruption of mitochondrial membrane potential, release of cytochrome c and Smac (second mitochondria-derived activator of caspase/direct IAP binding protein with low PI) from mitochondria, and activation of caspase 9. tBID 69-73 transcription factor 19 Homo sapiens 0-4