PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28026162-2	2017	Members of the antiapoptotic Bcl-2 proteins, including Bcl-2, Mcl-1, Bcl-xL, Bcl-w, and Bfl-1, inhibit apoptosis by selectively binding to conserved alpha-helical regions, named BH3 domains, of pro-apoptotic proteins such as Bim, tBid, Bad, or NOXA.	tBID	230-234	BCL2 related protein A1	Homo sapiens	88-93	
19228717-4	2009	It is controversial whether some BH3-domain proteins (Bim or tBid) directly activate multidomain pro-apoptotic proteins (e.g., Bax and Bak) or act via inhibition of those anti-apoptotic Bcl-2 proteins (Bcl-2, Bcl-XL, Bcl-w, Mcl-1, Bfl1/A-1, and Bcl-B) that stabilize pro-apoptotic proteins.	tBID	61-65	BCL2 related protein A1	Homo sapiens	231-235	
19228717-4	2009	It is controversial whether some BH3-domain proteins (Bim or tBid) directly activate multidomain pro-apoptotic proteins (e.g., Bax and Bak) or act via inhibition of those anti-apoptotic Bcl-2 proteins (Bcl-2, Bcl-XL, Bcl-w, Mcl-1, Bfl1/A-1, and Bcl-B) that stabilize pro-apoptotic proteins.	tBID	61-65	BCL2 related protein A1	Homo sapiens	236-239	
17724464-0	2008	Bfl-1/A1 functions, similar to Mcl-1, as a selective tBid and Bak antagonist.	tBID	53-57	BCL2 related protein A1	Homo sapiens	0-8	
17724464-3	2008	We demonstrate that in living cells Bfl-1 selectively interacts with Bak and tBid, but not with Bax or Bid.	tBID	77-81	BCL2 related protein A1	Homo sapiens	36-41	
17724464-5	2008	We also show that Bfl-1 blocks tumor necrosis factor-alpha (TNFalpha)-induced activation of Bax indirectly, via association with tBid.	tBID	129-133	BCL2 related protein A1	Homo sapiens	18-23	
17724464-6	2008	C-terminal deletion decreased Bfl-1"s interaction with Bak and tBid and reduced its ability to suppress Bak- and tBid-mediated cell death.	tBID	63-67	BCL2 related protein A1	Homo sapiens	30-35	
17724464-6	2008	C-terminal deletion decreased Bfl-1"s interaction with Bak and tBid and reduced its ability to suppress Bak- and tBid-mediated cell death.	tBID	113-117	BCL2 related protein A1	Homo sapiens	30-35	
17724464-8	2008	Bfl-1 associates with tBid to prevent activation of proapoptotic Bax and Bak, and it also interacts directly with Bak to antagonize Bak-mediated cell death, similar to Mcl-1.	tBID	22-26	BCL2 related protein A1	Homo sapiens	0-5	
11929871-9	2002	However, Bfl-1 remains tightly and selectively bound to tBid and blocks collaboration between tBid and Bax or Bak in the plane of the mitochondrial membrane, thereby preventing mitochondrial apoptotic activation.	tBID	56-60	BCL2 related protein A1	Homo sapiens	9-14	
11929871-9	2002	However, Bfl-1 remains tightly and selectively bound to tBid and blocks collaboration between tBid and Bax or Bak in the plane of the mitochondrial membrane, thereby preventing mitochondrial apoptotic activation.	tBID	94-98	BCL2 related protein A1	Homo sapiens	9-14