PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24793882-0 2014 Ruthenium(II) complexes as apoptosis inducers by stabilizing c-myc G-quadruplex DNA. Ruthenium(II) 0-13 MYC proto-oncogene, bHLH transcription factor Homo sapiens 61-66 28888786-0 2017 Microwave-assisted synthesis of ruthenium(II) complexes with alkynes as potential inhibitor by selectively recognizing c-myc G-quadruplex DNA. Ruthenium(II) 32-45 MYC proto-oncogene, bHLH transcription factor Homo sapiens 119-124 28888786-8 2017 Thus, these ruthenium(II) complexes can be developed as potential inhibitors in chemotherapy through their binding and stabilization of c-myc G-quadruplex DNA. Ruthenium(II) 12-25 MYC proto-oncogene, bHLH transcription factor Homo sapiens 136-141 25988535-2 2015 It was found that these ruthenium(II) complexes exhibited considerable in vitro anticancer activities and that they were the effective stabilizers of telomeric and G-quadruplex-DNA (G4-DNA) in promoter of c-myc, which acted as a telomerase inhibitor targeting G4-DNA and induced cell senescence and apoptosis. Ruthenium(II) 24-37 MYC proto-oncogene, bHLH transcription factor Homo sapiens 205-210 24793882-6 2014 In a word, this type of ruthenium(II) complexes can act as potential apoptosis inducers with low toxicity in clinic by stabilizing c-myc G4 DNA. Ruthenium(II) 24-37 MYC proto-oncogene, bHLH transcription factor Homo sapiens 131-136