PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29147666-9 2017 In conclusion, 6-OHDA delays reepithelialization during wound healing in diabetic mice by decreasing EGF, but increases wound contraction by reducing IL-1beta levels and the number of MCs. Oxidopamine 15-21 interleukin 1 beta Mus musculus 150-158 11244300-5 2001 First we confirmed that PVN 6-hydroxydopamine lesions, which selectively depleted catecholaminergic terminals, significantly reduced IL-1beta-induced mPVN CRH cell activation. Oxidopamine 28-45 interleukin 1 beta Mus musculus 133-141 10462192-8 1999 Mice in which cerebral norepinephrine was depleted with DSP-4 or 6-hydroxydopamine also displayed the usual hypophagia in response to mIL-1beta and LPS. Oxidopamine 65-82 interleukin 1 beta Mus musculus 134-143 29054324-5 2018 6-OHDA administration elevated levels of tumour necrosis factor-alpha, interferon-gamma, interleukin-1beta, interleukin-2, interleukin-6 and nuclear factor-kappa B and decreased the interleukin-10 levels, total reactive antioxidant potential and total antioxidant reactivity in striatum, as well as, modified the calcium-binding protein B (S100B), brain-derived neurotrophic factor, nerve growth factor and glial cell line-derived neurotrophic factor levels. Oxidopamine 0-6 interleukin 1 beta Mus musculus 89-106 28726961-7 2017 Furthermore, the levels of oxidative stress, tumor necrosis factor (TNF)-alpha and interleukin (IL)-1beta are all reduced significantly in PD mice and the CAR-25 mg kg-1 DA group in comparison with that in 6-OHDA-lesioned mice with saline and 6-OHDA-lesioned mice, as well as the Tyrosine hydroxylase-immunoreactive (TH-ir) density increased (p < 0.01). Oxidopamine 243-249 interleukin 1 beta Mus musculus 83-105 30078232-9 2018 The Rev-erbalpha knockout mice showed prolonged microglial activation in the SN along with the overproduction of interleukin 1beta, a pro-inflammatory cytokine, in response to 6-OHDA. Oxidopamine 176-182 interleukin 1 beta Mus musculus 113-130 28247333-5 2017 Our results indicate that treatment with 6-OHDA promotes microglial polarization toward the M1 state in BV2 microglia cells by increasing the release of interleukin (IL)-6, IL-1beta, or tumor necrosis factor-alpha, which can be prevented by pretreatment with DEX. Oxidopamine 41-47 interleukin 1 beta Mus musculus 173-181