PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30361093-7	2018	We demonstrated that expressions of HRD1 and Suppressor/Enhancer Lin12 1-like (SEL1L: a HRD1 stabilizer) increased in SH-SY5Y human neuroblastoma cells upon exposure to 6-hydroxydopamine (6-OHDA).	Oxidopamine	169-186	synoviolin 1	Homo sapiens	36-40	
23710284-4	2013	Moreover, upregulation of HRD1 by the antiepileptic drug zonisamide suppresses 6-hydroxydopamine-induced neuronal cell death.	Oxidopamine	79-96	synoviolin 1	Homo sapiens	26-30	
30361093-7	2018	We demonstrated that expressions of HRD1 and Suppressor/Enhancer Lin12 1-like (SEL1L: a HRD1 stabilizer) increased in SH-SY5Y human neuroblastoma cells upon exposure to 6-hydroxydopamine (6-OHDA).	Oxidopamine	169-186	synoviolin 1	Homo sapiens	88-92	
30361093-7	2018	We demonstrated that expressions of HRD1 and Suppressor/Enhancer Lin12 1-like (SEL1L: a HRD1 stabilizer) increased in SH-SY5Y human neuroblastoma cells upon exposure to 6-hydroxydopamine (6-OHDA).	Oxidopamine	188-194	synoviolin 1	Homo sapiens	36-40	
30361093-7	2018	We demonstrated that expressions of HRD1 and Suppressor/Enhancer Lin12 1-like (SEL1L: a HRD1 stabilizer) increased in SH-SY5Y human neuroblastoma cells upon exposure to 6-hydroxydopamine (6-OHDA).	Oxidopamine	188-194	synoviolin 1	Homo sapiens	88-92	
30361093-8	2018	The 6-OHDA-induced cell death was suppressed in cells overexpressing wt-HRD1, whereas cell death was enhanced in cells with knockdown of HRD1 expression.	Oxidopamine	4-10	synoviolin 1	Homo sapiens	72-76	
30361093-9	2018	These results suggest that HRD1 is a key molecule involved in 6-OHDA-induced cell death.	Oxidopamine	62-68	synoviolin 1	Homo sapiens	27-31	
30361093-11	2018	As a result, 6-OHDA-induced cell death was enhanced in cells suppressing SEL1L expression, and this cell death was much more evident than that in cells with suppression of HRD1 expression.	Oxidopamine	13-19	synoviolin 1	Homo sapiens	172-176	
30361093-12	2018	These findings strongly indicate that SEL1L is necessary for maintaining and stabilizing the amount of HRD1 protein, and stabilizing the amount of HRD1 protein through SEL1L may serve to protect against 6-OHDA-induced cell death.	Oxidopamine	203-209	synoviolin 1	Homo sapiens	147-151	
30361093-15	2018	This intracellular transduction may suppress the enhancement of 6-OHDA-induced cell death caused by the loss of HRD1.	Oxidopamine	64-70	synoviolin 1	Homo sapiens	112-116