PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31705926-4	2020	The neurotoxin 6-hydroxydopamine (6-OHDA) treated with SH-SY5Y cells decreased OPA1 and mitofusin 2 fusion proteins, but increased fission 1 and dynamin related protein 1 (DRP1) fission proteins.	Oxidopamine	15-32	dynamin 1 like	Homo sapiens	145-170	
31705926-4	2020	The neurotoxin 6-hydroxydopamine (6-OHDA) treated with SH-SY5Y cells decreased OPA1 and mitofusin 2 fusion proteins, but increased fission 1 and dynamin related protein 1 (DRP1) fission proteins.	Oxidopamine	15-32	dynamin 1 like	Homo sapiens	172-176	
31705926-4	2020	The neurotoxin 6-hydroxydopamine (6-OHDA) treated with SH-SY5Y cells decreased OPA1 and mitofusin 2 fusion proteins, but increased fission 1 and dynamin related protein 1 (DRP1) fission proteins.	Oxidopamine	34-40	dynamin 1 like	Homo sapiens	145-170	
31705926-4	2020	The neurotoxin 6-hydroxydopamine (6-OHDA) treated with SH-SY5Y cells decreased OPA1 and mitofusin 2 fusion proteins, but increased fission 1 and dynamin related protein 1 (DRP1) fission proteins.	Oxidopamine	34-40	dynamin 1 like	Homo sapiens	172-176	
22846607-8	2013	Addition of 6-OHDA did not increase the levels of fission 1, mitofusins 1 and 2 or optic atrophy 1 proteins, but does lead to the translocation of dynamin related protein 1 from the cytosol to the mitochondria.	Oxidopamine	12-18	dynamin 1 like	Homo sapiens	147-172	
18395527-0	2008	6-Hydroxydopamine (6-OHDA) induces Drp1-dependent mitochondrial fragmentation in SH-SY5Y cells.	Oxidopamine	0-17	dynamin 1 like	Homo sapiens	35-39	
18395527-0	2008	6-Hydroxydopamine (6-OHDA) induces Drp1-dependent mitochondrial fragmentation in SH-SY5Y cells.	Oxidopamine	19-25	dynamin 1 like	Homo sapiens	35-39	
18395527-3	2008	By immunofluorescence and time-lapse fluorescence microscopy we demonstrated that 6-OHDA induced profound mitochondrial fragmentation in SH-SY5Y cells, an event that was similar to mitochondrial fission induced by overexpression of Fis1p, a membrane adaptor for the dynamin-related protein 1 (DLP1/Drp1).	Oxidopamine	82-88	dynamin 1 like	Homo sapiens	266-291	
18395527-3	2008	By immunofluorescence and time-lapse fluorescence microscopy we demonstrated that 6-OHDA induced profound mitochondrial fragmentation in SH-SY5Y cells, an event that was similar to mitochondrial fission induced by overexpression of Fis1p, a membrane adaptor for the dynamin-related protein 1 (DLP1/Drp1).	Oxidopamine	82-88	dynamin 1 like	Homo sapiens	293-297	
18395527-3	2008	By immunofluorescence and time-lapse fluorescence microscopy we demonstrated that 6-OHDA induced profound mitochondrial fragmentation in SH-SY5Y cells, an event that was similar to mitochondrial fission induced by overexpression of Fis1p, a membrane adaptor for the dynamin-related protein 1 (DLP1/Drp1).	Oxidopamine	82-88	dynamin 1 like	Homo sapiens	298-302	
18395527-6	2008	Silencing of DLP1/Drp1, which is involved in mitochondrial and peroxisomal fission, prevented 6-OHDA-induced fragmentation of mitochondria.	Oxidopamine	94-100	dynamin 1 like	Homo sapiens	13-17	
18395527-6	2008	Silencing of DLP1/Drp1, which is involved in mitochondrial and peroxisomal fission, prevented 6-OHDA-induced fragmentation of mitochondria.	Oxidopamine	94-100	dynamin 1 like	Homo sapiens	18-22	
18395527-7	2008	Furthermore, in cells silenced for Drp1, 6-OHDA-induced cell death was reduced, indicating that a block in mitochondrial fission protects SH-SY5Y cells against 6-OHDA toxicity.	Oxidopamine	41-47	dynamin 1 like	Homo sapiens	35-39	
18395527-7	2008	Furthermore, in cells silenced for Drp1, 6-OHDA-induced cell death was reduced, indicating that a block in mitochondrial fission protects SH-SY5Y cells against 6-OHDA toxicity.	Oxidopamine	160-166	dynamin 1 like	Homo sapiens	35-39	
18395527-9	2008	Our data demonstrate for the first time an involvement of mitochondrial fragmentation and Drp1 function in 6-OHDA-induced apoptosis.	Oxidopamine	107-113	dynamin 1 like	Homo sapiens	90-94	
22821850-4	2012	Upon 6-OHDA treatment, dynamin-related protein 1 (Drp1) transiently translocated to mitochondria, with increased levels of mitochondrial Drp1 being observed after 3 and 9h.	Oxidopamine	5-11	dynamin 1 like	Homo sapiens	23-48	
22821850-4	2012	Upon 6-OHDA treatment, dynamin-related protein 1 (Drp1) transiently translocated to mitochondria, with increased levels of mitochondrial Drp1 being observed after 3 and 9h.	Oxidopamine	5-11	dynamin 1 like	Homo sapiens	50-54	
22821850-4	2012	Upon 6-OHDA treatment, dynamin-related protein 1 (Drp1) transiently translocated to mitochondria, with increased levels of mitochondrial Drp1 being observed after 3 and 9h.	Oxidopamine	5-11	dynamin 1 like	Homo sapiens	137-141